6種類目のゲノム由来ヌクレオシド 5-hmdC

文献

• The Discovery of 5-Formylcytosine in Embryonic Stem Cell DNA
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• 5-Hydroxymethylcytosine, the Sixth Base of the Genome (Minireview)
  • M. Münzel, D. Globisch, T. Carell, Angew. Chem. Int. Ed. 2011, 50, 6460.
• 5-Hydroxymethylcytosine Is Strongly Depleted in Human Cancers but Its Levels Do Not Correlate with IDH1 Mutations
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• Determination of genomic 5-hydroxymethyl-2'-deoxycytidine in human DNA by capillary electrophoresis with laser-induced fluorescence
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• Discrimination between 5-hydroxymethylcytosine and 5-methylcytosine in DNA by selective chemical labeling
  • J. Hu, Y. Chen, X. Xu, F. Wu, X. Xing, Z. Xu, J. Xu, X. Weng, X. Zhou, Bioorg. Med. Chem. Lett. 2014, 24, 294.
• Deamination, Oxidation, and C–C Bond Cleavage Reactivity of 5-Hydroxymethylcytosine, 5-Formylcytosine, and 5-Carboxycytosine
  • S. Schiesser, T. Pfaffeneder, K. Sadeghian, B. Hackner, B. Steigenberger, A. S. Schröder, J. Steinbacher, G. Kashiwazaki, G. Höfner, K. T. Wanner, C. Ochsenfeld, T. Carell, J. Am. Chem. Soc. 2013, 135, 14593.

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