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CAS RN: 51012-33-0 | Product Number: T3600
Tiapride Hydrochloride
Purity: >99.0%(T)(HPLC)
Synonyms:
- N-[2-(Diethylamino)ethyl]-2-methoxy-5-(methylsulfonyl)benzamide Hydrochloride
Product Documents:
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Product Number | T3600 |
Purity / Analysis Method | >99.0%(T)(HPLC) |
Molecular Formula / Molecular Weight | C__1__5H__2__4N__2O__4S·HCl = 364.89 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Refrigerated (0-10°C) |
Condition to Avoid | Heat Sensitive |
Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image), 250MG-Glass Bottle with Plastic Insert (View image) |
CAS RN | 51012-33-0 |
Related CAS RN | 51012-32-9 |
Reaxys Registry Number | 4341690 |
PubChem Substance ID | 354335068 |
Merck Index (14) | 9421 |
MDL Number | MFCD00133861 |
Specifications
Appearance | White to Almost white powder to crystal |
Purity(HPLC) | min. 99.0 area% |
Purity(Nonaqueous Titration) | min. 99.0 % |
Properties (reference)
Solubility (slightly sol. in) | Methanol |
GHS
Related Laws:
Transport Information:
H.S.code* | 2930.90-900 |
Application
Tiapride Hydrochloride: A Selective D2 Dopamine Subtype Receptors Antagonist
Tiapride hydrochloride is a selective D2 dopamine subtype receptors antagonist without any affinity for subtype receptors of the principal central neurotransmitters, such as serotonin [S0370], noradrenaline [A0906] and histamine [H0146]. Tiapride belongs to the benzamide type neuroleptics, which all may share unwanted effects, hyperprolactinemia and QT-interval prolongation. (The product is for research purpose only.)
References
- Comparison of Effects of Tiapride and Sulpiride on D-1, D-2, D-3 and D-4 Subtypes of Dopamine Receptors in Rat Striatal and Bovine Caudate Nucleus Membranes
- Actions of sulpiride and tiapride in a simple model of anxiety in mice
- The benzamide tiapride: treatment of extrapyramidal motor and other clinical syndromes (a review)
- Direct determination of benzamides in serum by column-switching high-performance liquid chromatography
- Simultaneous electrochemiluminescence determination of sulpiride and tiapride by capillary electrophoresis with cyclodextrin additives
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