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CAS RN: 920-66-1 | Product Number: H1793
1,1,1,3,3,3-Hexafluoropropan-2-ol [for HPLC]
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Purity: >99.5%(GC)
Synonyms:
- 1,1,1,3,3,3-Hexafluoro-2-propanol
- 1,1,1,3,3,3-Hexafluoroisopropyl Alcohol
- HFP
- HFIP
Product Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
|---|---|---|---|---|---|
| 100G |
$219.00
|
≥40 | Contact Us | 23 |
|
* Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact TCI for lead times on items not in stock. Excludes regulated items and items that ship on ice.
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*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | H1793 |
| Purity / Analysis Method | >99.5%(GC) |
| Molecular Formula / Molecular Weight | C__3H__2F__6O = 168.04 |
| Physical State (20 deg.C) | Liquid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 920-66-1 |
| Reaxys Registry Number | 1841007 |
| PubChem Substance ID | 468592052 |
| SDBS (AIST Spectral DB) | 5259 |
| MDL Number | MFCD00011651 |
Specifications
| Appearance | Colorless to Almost colorless clear liquid |
| Purity(GC) | min. 99.5 % |
| Absorbance(210nm) | max. 0.800 |
| Absorbance(220nm) | max. 0.400 |
| Absorbance(230nm) | max. 0.200 |
| Absorbance(254nm) | max. 0.080 |
| Absorbance(400nm) | max. 0.030 |
| Water | max. 0.5 % |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | -4 °C |
| Boiling Point | 58 °C |
| Specific Gravity (20/20) | 1.62 |
| Refractive Index | 1.28 |
| Solubility in water | Soluble |
| Solubility (soluble in) | Ether, Acetone |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H302 + H332 : Harmful if swallowed or if inhaled. H314 : Causes severe skin burns and eye damage. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray. P270 : Do not eat, drink or smoke when using this product. P271 : Use only outdoors or in a well-ventilated area. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P303 + P361 + P353 : IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower. P301 + P330 + P331 : IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P363 : Wash contaminated clothing before reuse. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. P304 + P340 + P310 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/doctor. P305 + P351 + P338 + P310 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER/doctor. P405 : Store locked up. |
Related Laws:
| RTECS# | UB6450000 |
Transport Information:
| UN Number (DOT-AIR) | UN1760 |
| Class (DOT-AIR) | 8 |
| Packing Group (TCI-A) | III |
| HS Number | 2905.29.9000 |
Application
Buffer and Additives for LC Analysis of Oligonucleotides
References
- Separation of small DNA and RNA oligonucleotides by high-performance anion-exchange liquid chromatography
- Analysis of oligonucleotides by HPLC-electrospray ionization mass spectrometry
Application
1,1,1,3,3,3-Hexafluoropropan-2-ol: An Acidic Modifier in Buffers for Mobile Phases for Liquid Chromatography
1,1,1,3,3,3-Hexafluoropropan-2-ol (HFIP or HFP) has been used not only as a solvent but also as an acidic modifier in buffers for mobile phases for liquid chromatography (HPLC). This product has defined specifications suitable for HPLC measurements, such as absorbance data.
References
- Analysis of Oligonucleotides by HPLC-Electrospray Ionization Mass Spectrometry
- New procedure for the use of high-performance liquid chromatography-electrospray ionization mass spectrometry for the analysis of nucleotides and oligonucleotides
- A. Apffel, J. A. Chakel, S. Fischer, K. Lichtenwalter, W. S. Hancock, J. Chromatogr. A 1997, 777, 3.
- Ion-pair reversed-phase high-performance liquid chromatography analysis of oligonucleotides: Retention prediction
- The Role of Fluorinated Alcohols as Mobile Phase Modifiers for LC-MS Analysis of Oligonucleotides
Articles/Brochures
TCIMAIL
[Product Highlights] Buffer and Additives for LC Analysis of Oligonucleotides[TCIMAIL No.192] Guaranteed Analytical Reagents for Oligonucleotides
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
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Specifications
C of A & Other Certificates
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Analytical Charts
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Other Documents
Related Products
1,1,1,3,3,3-Hexafluoropropan-2-ol
| Product # | H0424 |
| CAS RN | 920-66-1 |
| Purity / Analysis Method: | >99.0%(GC) |