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CAS RN: 920-66-1 | Product Number: H0424
1,1,1,3,3,3-Hexafluoropropan-2-ol
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Purity: >99.0%(GC)
Synonyms:
- 1,1,1,3,3,3-Hexafluoro-2-propanol
- 1,1,1,3,3,3-Hexafluoroisopropyl Alcohol
- HFP
- HFIP
Product Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
|---|---|---|---|---|---|
| 25G |
$81.00
|
≥80 | 25 | ≥100 |
|
| 100G |
$270.00
|
≥80 | ≥40 | ≥100 |
|
| 500G |
$829.00
|
Contact Us | ≥60 | ≥100 |
|
* Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact TCI for lead times on items not in stock. Excludes regulated items and items that ship on ice.
* To send your quote request for bulk quantities, please click on the "Request Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | H0424 |
| Purity / Analysis Method | >99.0%(GC) |
| Molecular Formula / Molecular Weight | C__3H__2F__6O = 168.04 |
| Physical State (20 deg.C) | Liquid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 920-66-1 |
| Reaxys Registry Number | 1841007 |
| PubChem Substance ID | 87570824 |
| SDBS (AIST Spectral DB) | 5259 |
| MDL Number | MFCD00011651 |
Specifications
| Appearance | Colorless to Almost colorless clear liquid |
| Purity(GC) | min. 99.0 % |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | -4 °C |
| Boiling Point | 58 °C |
| Specific Gravity (20/20) | 1.62 |
| Refractive Index | 1.28 |
| Maximum Absorption Wavelength | 229 nm |
| Solubility in water | Soluble |
| Solubility (soluble in) | Ether, Acetone |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H302 + H332 : Harmful if swallowed or if inhaled. H314 : Causes severe skin burns and eye damage. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray. P270 : Do not eat, drink or smoke when using this product. P271 : Use only outdoors or in a well-ventilated area. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P303 + P361 + P353 : IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower. P301 + P330 + P331 : IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P363 : Wash contaminated clothing before reuse. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. P304 + P340 + P310 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/doctor. P305 + P351 + P338 + P310 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER/doctor. P405 : Store locked up. |
Related Laws:
| RTECS# | UB6450000 |
Transport Information:
| UN Number (DOT-AIR) | UN1760 |
| Class (DOT-AIR) | 8 |
| Packing Group (TCI-A) | III |
| HS Number | 2905.59.1000 |
Application
1,1,1,3,3,3-Hexafluoro-2-propanol (HFIP or HFP): A Solvent with Specific Properties
1,1,1,3,3,3-Hexafluoro-2-propanol (HFIP or HFP) is used as a solvent with specific properties. Its combination of high H bonding donor ability, low nucleophilicity, and high ionizing power allows reactions to proceed under mild conditions, which usually require the use of added reagents or metal catalysts to be carried out. In addition, HFIP is used as acid in volatile buffers for ion pair HPLC.
References
- Fluorinated alcohols: A new medium for selective and clean reaction (a review)
- 1,1,1,3,3,3-Hexafluoro-2-propanol (a review of the properties, handling and applications)
- 1,1,1,3,3,3-Hexafluoro-2-propanol for the removal of the 4,4'-dimethoxytrityl protecting group from the 5'-hydroxyl of acid-sensitive nucleosides and nucleotides
- New TFA-Free Cleavage and Final Deprotection in Fmoc Solid-Phase Peptide Synthesis: Dilute HCl in Fluoro Alcohol
- Making radical cations live longer
- Analysis of Oligonucleotides by HPLC-Electrospray Ionization Mass Spectrometry
PubMed Literature
Articles/Brochures
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
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Specifications
C of A & Other Certificates
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Analytical Charts
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Other Documents
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1,1,1,3,3,3-Hexafluoropropan-2-ol [for HPLC]
| Product # | H1793 |
| CAS RN | 920-66-1 |
| Purity / Analysis Method: | >99.5%(GC) |