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CAS RN: 749886-87-1 | 產品號碼: M2734
4-Methyl-N1-(3-phenylpropyl)-1,2-phenylenediamine
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產品規格
Appearance | White to Light yellow to Light orange powder to crystal |
Purity(GC) | min. 98.0 % |
Melting point | 101.0 to 105.0 °C |
NMR | confirm to structure |
性質
熔點 | 103 °C |
GHS
圖形表示 | |
信號詞 | Warning |
危險性說明 | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
防範說明 | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
相關法規
運輸資料
HS編碼* | 2921.59-000 |
Application
核内因子κB (NFκB) 活性化阻害剤
This compound, often called as JSH-23, is an inhibitor of nuclear factor-κB (NFκB) transcriptional activity (IC50= 7.1 µM). NFκB is a protein complex controls transcription of DNA and inflammatory cytokine production. JSH-23 has been reported to inhibit lipopolysaccharide(LPS)-induced nuclear translocation of NFκB without affecting the process of NFκB - IκB complex degradation.
References
- Inhibitory action of novel aromatic diamine compound on lipopolysaccharide-induced nuclear translocation of NF-κB without affecting IκB degradation
- Hypoxia-inducible factors 1 and 2 are important transcriptional effectors in primary macrophages experiencing hypoxia
- JSH-23 targets nuclear factor-kappa B and reverses various deficits in experimental diabetic neuropathy: affect on neuroinflammation and antioxidant defence
考研文獻
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產品規格
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