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CAS RN: 122892-31-3 | 產品號碼: I0948
Itopride Hydrochloride
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| 產品號碼 | I0948 |
| 純度/分析方法 | >98.0%(T)(HPLC) |
| 分子式 / 分子量 | C__2__0H__2__6N__2O__4·HCl = 394.90 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件 | Refrigerated (0-10°C) |
| 應避免的情況 | Heat Sensitive |
| 包裝和容器 | 1G-Glass Bottle with Plastic Insert （閲覽圖片） |
| CAS RN | 122892-31-3 |
| 相關CAS RN | 122898-67-3 |
| Reaxys-RN | 5369226 |
| PubChem Substance ID | 253662451 |
| Merck Index(14) | 5244 |
| MDL編號 | MFCD00881710 |
產品規格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 192.0 to 196.0 °C |
性質
| 熔點 | 194 °C |
| Maximum Wavelength | 258(MeOH) nm |
| 溶解性（微溶於） | Ethanol |
GHS
相關法規
| RTECS # | CV4552000 |
運輸資料
| HS編碼* | 2924.29-000 |
Application
Itopride Hydrochloride: A Water Soluble D2-Dopamine Receptor Antagonist
Itopride hydrochloride (HSR-803) is a water soluble D2-dopamine receptor antagonist and has a gastrokinetic effect. (The product is for research purpose only.)
References
- A novel water-soluble dopamine-2 antagonist with anticholinesterase activity in gastrointestinal motor activity. Comparison with domperidone and neostigmine
- Gastroprokinetic effect of a new benzamide derivative itopride and its action mechanisms in conscious dogs
- The involvement of flavin-containing monooxygenase but not CYP3A4 in metabolism of itopride hydrochloride, a gastroprokinetic agent: comparison with cisapride and mosapride citrate
- Stimulatory action of itopride hydrochloride on colonic motor activity in vitro and in vivo
- Chromatographic determination of itopride hydrochloride in the presence of its degradation products
- Determination of pantoprazole, rabeprazole, esomeprazole, domperidone and itopride in pharmaceutical products by reversed phase liquid chromatography using single mobile phase
考研文獻
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