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CAS RN: 54-42-2 | 產品號碼: I0258
5-Iodo-2'-deoxyuridine
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補充產品訊息:
This product is a sample for RUO (research use only). Do not use this product for any purpose other than testing and research.
| 產品號碼 | I0258 |
| 純度/分析方法 | >99.0%(T) |
| 分子式 / 分子量 | C__9H__1__1IN__2O__5 = 354.10 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件 | Room Temperature (Recommended in a cool and dark place, <15°C) |
| 儲存在惰性氣體下 | Store under inert gas |
| 應避免的情況 | Light Sensitive,Air Sensitive |
| 包裝和容器 | 1G-Glass Bottle with Plastic Insert （閲覽圖片） |
| CAS RN | 54-42-2 |
| Reaxys-RN | 30397 |
| PubChem Substance ID | 87571623 |
| SDBS (AIST Spectral DB) | 4820 |
| Merck Index(14) | 4891 |
| MDL編號 | MFCD00134656 |
產品規格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 99.0 % |
| Specific rotation [a]20/D | +28.0 to +31.0 deg(C=1, 1mol/L NaOH sol.) |
| Solubility in hot Water | almost transparency |
性質
| 比旋光 [α]D | 30° (C=1,1mol/L NaOH sol.) |
GHS
| 圖形表示 |
|
| 信號詞 | Warning |
| 危險性說明 | H302 + H312 + H332 : Harmful if swallowed, in contact with skin or if inhaled. H315 : Causes skin irritation. H319 : Causes serious eye irritation. H361 : Suspected of damaging fertility or the unborn child. H341 : Suspected of causing genetic defects. |
| 防範說明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray. P270 : Do not eat, drink or smoke when using this product. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P271 : Use only outdoors or in a well-ventilated area. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. P302 + P352 + P312 : IF ON SKIN: Wash with plenty of water.Call a POISON CENTER/doctor if you feel unwell. P304 + P340 + P312 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor if you feel unwell. P405 : Store locked up. |
相關法規
| RTECS # | YU7700000 |
運輸資料
| HS編碼* | 2934.99-000 |
Application
Idoxuridine: A Thymidine Analog and an Antiviral Agent against Herpes Simplex Virus (HSV)
Idoxuridine is a thymidine analog that is used as an antiviral agent against herpes simplex virus (HSV). Idoxuridine has a chemical structure similar to thymidine, except that the 5-methyl group is replaced by iodine. Herpes simplex virus utilizes thymidine in the synthesis of deoxyribonucleic acid (DNA). When idoxuridine is substituted for thymidine in the viral DNA, the viral is unable to replicate its DNA. (The product is for research purpose only.)
References
- Synthesis and biological activities of iododeoxyuridine, an analog of thymidine
- The effects of incorporation of 5-halogenated deoxyuridines into the DNA of eukaryotic cells (a review)
- Specific targets for antiviral drugs (a review)
考研文獻
文章/手冊
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