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CAS RN: 660-27-5 | 產品號碼: D5074
Diisopropylamine Dichloroacetate
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* TCI會時常優化儲存條件,儲存溫度請以在線目錄為準，敬請留意。
| 產品號碼 | D5074 |
| 純度/分析方法 | >98.0%(T) |
| 分子式 / 分子量 | C__6H__1__5N·C__2H__2Cl__2O__2 = 230.13 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件 | Room Temperature (Recommended in a cool and dark place, <15°C) |
| 包裝和容器 | 1G-Glass Bottle with Plastic Insert （閲覽圖片） |
| CAS RN | 660-27-5 |
| Reaxys-RN | 4158968 |
| PubChem Substance ID | 354333577 |
| Merck Index(14) | 3197 |
| MDL編號 | MFCD00868288 |
產品規格
| Appearance | White to Almost white powder to crystal |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 120.0 to 124.0 °C |
性質
| 熔點 | 122 °C |
| 溶解性（可溶於） | Methanol |
GHS
| 圖形表示 |
|
| 信號詞 | Warning |
| 危險性說明 | H302 : Harmful if swallowed. H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| 防範說明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
相關法規
| RTECS # | AG6475000 |
運輸資料
| HS編碼* | 2921.19-000 |
Application
Diisopropylamine Dichloroacetate: An Active Component of Pangamic Acid (Once Called "Vitamin B15")
Diisopropylamine dichloroacetate (abbrev.: DADA or DIPA) is an active component of pangamic acid (once called "vitamin B15") which was first isolated from apricot seeds by Krebs et al. in 1951. In 1958, Casu et al. revealed that pangamic acid is a mixture of DADA, sodium gluconate [G0041] and glycine [G0099]. And then, DADA has received attention for its pharmacologic and therapeutic effects, especially on hepatic function. (The product is for research purpose only.)
References
- Pangamic acid sodium: a newly isolated crystalline water-soluble factor; a preliminary report.
- Analysis of commercial samples of vitamin B15
- Review of the pharmacologic and therapeutic effects of diisopropylammonium dichloroacetate (DIPA) (a review)
- Diisopropylammonium dichloroacetate (DIPA) and sodium dichloroacetate (DCA): Effect on glucose and fat metabolism in normal and diabetic tissue
- Pangamic acid vitamin B15 (a review)
- Diisopropylamine dichloroacetate, a novel pyruvate dehydrogenase kinase 4 inhibitor, as a potential therapeutic agent for metabolic disorders and multiorgan failure in severe influenza
考研文獻
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