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CAS RN: 78351-75-4 | 產品號碼: C2884
1-(3-Chloroanilino)-4-phenylphthalazine
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| 包裝 | 價格 | 同一天 | 2-3个工作日 |
|---|---|---|---|
| 20MG |
NT$2,120
|
20 | 2 |
| 100MG |
NT$7,280
|
29 | 1 |
* 以上價格已含運費關稅等但一些需要海運以及乾冰運輸的產品除外,詳情請與
當地經銷商
洽詢。
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| 產品號碼 | C2884 |
| 純度/分析方法 | >98.0%(GC) |
| 分子式 / 分子量 | C__2__0H__1__4ClN__3 = 331.80 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件 | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 78351-75-4 |
| PubChem Substance ID | 253661527 |
| MDL編號 | MFCD00209838 |
產品規格
| Appearance | White to Light yellow powder to crystal |
| Purity(GC) | min. 98.0 % |
| NMR | confirm to structure |
性質
GHS
相關法規
運輸資料
| HS編碼* | 2933.99-000 |
Application
MY-5445: A Specific Inhibitor of Cyclic GMP Phosphodiesterase Type 5 (PDE5)
1-(3-Chloroanilino)-4-phenylphthalazine (MY-5445) is a specific inhibitor of cyclic GMP (cGMP) phosphodiesterase type 5 (PDE5). MY-5445 inhibits platelet aggregation by increasing cGMP content.
References
Effect of 1-(3-chloroanilino)-4-phenylphthalazine (MY-5445), a specific inhibitor of cyclic GMP phosphodiesterase, on human platelet aggregation
M. Hagiwara, T. Endo, T. Kanayama, H. Hidaka, J. Pharmacol. Exp. Ther. 1984, 228, 467.
Role of selective cyclic GMP phosphodiesterase inhibition in the myorelaxant actions of M&B 22,948, MY-5445, vinpocetine and 1-methyl-3-isobutyl-8-(methylamino)xanthine
J. E. Souness, R. Brazdil, B. K. Diocee, R. Jordan, Br. J. Pharmacol. 1989, 98, 725.
Exisulind induction of apoptosis involves guanosine 3',5'-cyclic monophosphate phosphodiesterase inhibition, protein kinase G activation, and attenuated β-catenin
Phosphodiesterase Type 5 Is Highly Expressed in the Hypertrophied Human Right Ventricle, and Acute Inhibition of Phosphodiesterase Type 5 Improves Contractility
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