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CAS RN: 989-51-5 | Product Number: E0694
(-)-Epigallocatechin Gallate Hydrate
Purity: >98.0%(HPLC)
Synonyms:
- EGCG Hydrate
- (-)-cis-3,4-Dihydro-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-1(2H)-benzopyran-3-yl Gallate Hydrate
Product Documents:
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Product Number | E0694 |
Purity / Analysis Method | >98.0%(HPLC) |
Molecular Formula / Molecular Weight | C__2__2H__1__8O__1__1·xH__2O = 458.38 (as Anhydrous) |
Physical State (20 deg.C) | Solid |
Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
Store Under Inert Gas | Store under inert gas |
Condition to Avoid | Light Sensitive,Air Sensitive |
Packaging and Container | 100MG-Glass Bottle with Plastic Insert (View image), 500MG-Glass Bottle with Plastic Insert (View image) |
CAS RN | 989-51-5 |
Related CAS RN | 1257-08-5 |
Reaxys Registry Number | 67944 |
PubChem Substance ID | 87558853 |
Merck Index (14) | 3526 |
MDL Number | MFCD00075940 |
Specifications
Appearance | White to Light yellow to Light orange powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Specific rotation [a]20/D | -165.0 to -186.0 deg(C=1, EtOH) |
Water | max. 5.0 % |
Properties (reference)
Melting Point | 212 °C |
Specific Rotation | -176° (C=1,EtOH) |
Solubility (soluble in) | Ethanol |
GHS
Related Laws:
RTECS# | KB5200000 |
Transport Information:
H.S.code* | 2932.99-000 |
Application
Type III secretion system (T3SS) research / Type III secretion system (T3SS) inhibitor
References
- Epigallocatechin gallate inhibits the type III secretion system of Gram-negative enteropathogenic bacteria under model conditions
- Epigallocatechin-3-gallate inhibits bacterial virulence and invasion of host cells
Application
(-)-Epigallocatechin Gallate (EGCG): A Polyphenolic Compound with Diverse Biological Activities including Anti-Cancer Effects
(-)-Epigallocatechin gallate (EGCG), a polyphenolic compound, is the ester of epigallocatechin [E1084] and gallic acid [G0011]. EGCG has been found in a variety of plants including green and black tea plants, and reported to have diverse biological activities including antioxidant, anti-cancer, anti-angiogenic and cardiovascular protective effects. (The product is for research purpose only.)
References
- Tea catechins and polyphenols: health effects, metabolism, and antioxidant functions (a review)
- Green tea catechin, epigallocatechin-3-gallate (EGCG): Mechanisms, perspectives and clinical applications (a review)
- Green tea and its anti-angiogenesis effects (a review)
- Absorption, metabolism, anti-cancer effect and molecular targets of epigallocatechin gallate (EGCG): An updated review
- Molecular understanding of Epigallocatechin gallate (EGCG) in cardiovascular and metabolic diseases (a review)
PubMed Literature
Articles/Brochures
TCIMAIL
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