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CAS RN: 86347-15-1 | 产品编码: M3314
Medetomidine Hydrochloride
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| 产品编码 | M3314 |
| 纯度/分析方法 | >98.0%(T)(HPLC) |
| 分子式/分子量 | C__1__3H__1__6N__2·HCl = 236.74 |
| 外观与形状（20°C） | 固体 |
| 储存温度 | 室温 (15°C以下阴凉干燥处) |
| 储存在惰性气体下 | 存放于惰性气体之中 |
| 应避免的情况 | 湿气 (吸湿) |
| 包装和容器 | 100MG-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 86347-15-1 |
| Reaxys-RN | 4890476 |
| PubChem物质ID | 468592404 |
| Merck Index (14) | 5787 |
| MDL编号 | MFCD06798319 |
技术规格
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 177.0 to 181.0 °C |
| Specific rotation [a]20/D | -1.0 to +1.0 deg(C=1, H2O) |
物性（参考值）
| 熔点 | 179 °C |
GHS
| 象形图 |
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| 信号词 | Warning |
| 危险性说明 | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| 防范说明 | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
相关法规
运输信息
| HS编码* | 2933.29-000 |
应用
Medetomidine Hydrochloride: A Potent α2-Adrenoceptor Agonist with Sedation and Analgesia
Medetomidine hydrochloride is a potent α2-adrenoceptor agonist which produces sedation and analgesia. Medetomidine is a mixture of R and S isomers, and the S form (or the D form known as dexmedetomidine hydrochloride [D5062]) is reported to be the active form. In animals, atipamezole (an α2-adrenoceptor antagonist) [A3259] is used for the reversal of the sedative and analgesic effects of the agonists, medetomidine and dexmedetomidine. (The product is for research purpose only.)
References
- Pharmacological profiles of medetomidine and its antagonist, atipamezole (a review)
- A review of the physiological effects of α2-agonists related to the clinical use of medetomidine in small animal practice
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