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CAS RN: 298-93-1 | 产品编码: M3297
MTT [for Biochemical Research]
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![MTT [for Biochemical Research]](/_ui/responsive/theme-tci/images/missing_product_zoom.jpg "MTT [for Biochemical Research]")
| 产品编码 | M3297 |
| 纯度/分析方法 | >97.0%(HPLC) |
| 分子式/分子量 | C__1__8H__1__6BrN__5S = 414.33 |
| 外观与形状（20°C） | 固体 |
| 储存温度 | 室温 (15°C以下阴凉干燥处) |
| 储存在惰性气体下 | 存放于惰性气体之中 |
| 应避免的情况 | 光,湿气 (吸湿) |
| 包装和容器 | 1G-Glass Bottle with Plastic Insert （查看图片）, 200MG-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 298-93-1 |
| Reaxys-RN | 3825277 |
| PubChem物质ID | 468592393 |
| SDBS (AIST Spectral DB) | 10829 |
| MDL编号 | MFCD00011964 |
技术规格
| Appearance | Light yellow to Brown powder to crystal |
| Purity(HPLC) | min. 97.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Functionality test | to pass test (by Abs method) |
| Sensitiveness | Colorimetric Test : Turn Red purple with 35ppm D-Glucose |
| NMR | confirm to structure |
物性（参考值）
| 熔点 | 195 °C(dec.) |
| 最大吸收波长 | 380(H2O) nm |
| 水溶性 | 微溶 |
| 在水中的溶解度 | 10,000 mg/l |
| 溶解性（微溶于） | 乙醇 |
GHS
| 象形图 |
|
| 信号词 | Warning |
| 危险性说明 | H315 : Causes skin irritation. H319 : Causes serious eye irritation. H341 : Suspected of causing genetic defects. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P405 : Store locked up. |
相关法规
| RTECS# | XF8060000 |
运输信息
| HS编码* | 2934.10-000 |
应用
Use of a tetrazolium/formazan assay (MTT assay) for cell growth assays
MTT, a tetrazolium salt, is widely used tool in cell biology for measuring cell proliferation and cytotoxicity, first reported by T. Mosmann in 1983.1) With mammalian cells, fractionation studies indicate that the reduced pyridine nucleotide cofactor (NADH) in active mitochondria, is responsible for reduction of MTT to a blue color formazan product.2) Therefore, the assay detects living, but not dead cells and the signal generated is dependent on the degree of activation of the cells.3)
References
- 1) Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
- 2) Mechanism of cellular 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) reduction
- 3) Tetrazolium dyes as tools in cell biology: new insights into their cellular reduction (a review)
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技术规格
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其他文件
相关产品
3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyltetrazolium Bromide
| 产品 | D0801 |
| CAS RN | 298-93-1 |
| 纯度/分析方法 | >98.0%(T) |