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CAS RN: 89226-75-5 | 产品编码: M2225
Manidipine Dihydrochloride
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纯度/分析方法: >98.0%(T)(HPLC)
别名：
- 盐酸马尼地平
- 1,4-二氢-2,6-二甲基-4-(3-硝基苯基)-3,5-吡啶二羧酸-2-[4-(二苯基甲基)-1-哌嗪基]乙基甲基酯二盐酸盐
- 2-[4-(二苯基甲基)-1-哌嗪基]乙基甲基-1,4-二氢-2,6-二甲基-4-(3-硝基苯基)-3,5-吡啶二甲酸酯二盐酸盐
- 马尼地平二盐酸盐
- 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 2-[4-(Diphenylmethyl)-1-piperazinyl]ethyl Methyl Ester Dihydrochloride
- 2-[4-(Diphenylmethyl)-1-piperazinyl]ethyl Methyl 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate Dihydrochloride
产品文档：
| 规格 | 单价 | 同一天 | 2-3个工作日 | 左侧以上货期 | 数量 |
货期信息
|
|---|---|---|---|---|---|---|
| 1G |
S$319.50
|
2 | 12 | 下单后约2周内可以发货 |
|
| 产品编码 | M2225 |
| 纯度/分析方法 | >98.0%(T)(HPLC) |
| 分子式/分子量 | C__3__5H__3__8N__4O__6·2HCl = 683.63 |
| 外观与形状（20°C） | 固体 |
| 储存温度 | 室温 (15°C以下阴凉干燥处) |
| 包装和容器 | 1G-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 89226-75-5 |
| 相关CAS RN | 89226-50-6 |
| Reaxys-RN | 5710369 |
| PubChem物质ID | 160871248 |
| Merck Index (14) | 5743 |
| MDL编号 | MFCD00896434 |
技术规格
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| NMR | confirm to structure |
物性（参考值）
| 熔点 | 211 °C(dec.) |
| 水溶性 | 不溶 |
GHS
| 象形图 |
|
| 信号词 | Danger |
| 危险性说明 | H301 + H311 + H331 : Toxic if swallowed, in contact with skin or if inhaled. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray. P270 : Do not eat, drink or smoke when using this product. P271 : Use only outdoors or in a well-ventilated area. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing. P361 + P364 : Take off immediately all contaminated clothing and wash it before reuse. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P302 + P352 + P312 : IF ON SKIN: Wash with plenty of water.Call a POISON CENTER/doctor if you feel unwell. P304 + P340 + P311 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor. P403 + P233 : Store in a well-ventilated place. Keep container tightly closed. P405 : Store locked up. |
相关法规
| RTECS# | US7975300 |
运输信息
| UN编号 | UN2811 |
| 类别 | 6.1 |
| 包装类别 | III |
| HS编码* | 2933.59-000 |
应用
Studies of Calcium Antagonists
References
- New 1,4-dihydropyridine derivatives with potent and long-lasting hypotensive effect
- Effects of 12 Ca2+ antagonists on multidrug resistance, MDR1-mediated transport and MDR1 mRNA expression
- Inhibitory potencies of 1,4-dihydropyridine calcium antagonists to P-glycoprotein-mediated transport: comparison with the effects on CYP3A4
- M. Katoh, M. Nakajima, H. Yamazaki, T. Yokoi, Pharm. Res. 2000, 17, 1189.
- Effect of calcium antagonists on glomerular arterioles in spontaneously hypertensive rats
参考文献
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