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CAS RN: 82-02-0 | 产品编码: K0039
Khellin
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| 产品编码 | K0039 |
| 纯度/分析方法 | >95.0%(GC) |
| 分子式/分子量 | C__1__4H__1__2O__5 = 260.25 |
| 外观与形状（20°C） | 固体 |
| 储存温度 | 室温 (15°C以下阴凉干燥处) |
| 包装和容器 | 1G-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 82-02-0 |
| Reaxys-RN | 263185 |
| PubChem物质ID | 87571971 |
| SDBS (AIST Spectral DB) | 16671 |
| Merck Index (14) | 5309 |
| MDL编号 | MFCD00005007 |
技术规格
| Appearance | White to Orange to Green powder to crystal |
| Purity(GC) | min. 95.0 % |
| Melting point | 150.0 to 154.0 °C |
| Solubility in hot Methanol | almost transparency |
物性（参考值）
| 熔点 | 152 °C |
GHS
| 象形图 |
|
| 信号词 | Danger |
| 危险性说明 | H301 : Toxic if swallowed. H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
相关法规
| RTECS# | LV1050000 |
运输信息
| UN编号 | UN2811 |
| 类别 | 6.1 |
| 包装类别 | III |
| HS编码* | 2932.99-000 |
应用
Khellin: A Mild Photosensitizer
Khellin, a naturally occurring furochromone, has a chemical structure similar to a photosensitizing agent psoralen [P2077] which has been reported to be an efficient agent for treating vitiligo and psoriasis when combined with UVA irradiation. Khellin has been reported to have phototherapeutic properties that are similar to those of the psoralens, but with substantially lower phototoxic effects and DNA mutation effects. As opposed to psoralens, khellin did not induce skin phototoxicity with UVA but it induced repigmentation similar to psoralens. (The product is for research purpose only.)
References
- Phototherapeutic, photobiologic, and photosensitizing properties of khellin
- Khellin, a naturally occurring furochromone, used for the photochemotherapy of skin diseases: mechanism of action
- Treatment of vitiligo with khellin liposomes, ultraviolet light and blister roof transplantation
参考文献
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