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CAS RN: 23672-07-3 | 产品编码: I0821
(S)-(-)-Sulpiride
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技术规格
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 185.0 to 189.0 °C |
| Specific rotation [a]20/D | -67.0 to -71.0 deg(C=3, DMF) |
物性（参考值）
| 熔点 | 187 °C |
| 比旋光度 [α]D | -69° (C=3,DMF) |
| 溶解性（可溶于） | 二甲基甲酰胺 |
GHS
相关法规
| RTECS# | BZ3400100 |
运输信息
| HS编码* | 2935.90-000 |
应用
(S)-(-)-Sulpiride: A Dopamine D2 Receptor Antagonist
(S)-(-)-Sulpiride (or levosulpiride) is the active enantiomer of (±)-sulpiride [S0501], and a substituted benzamide-type atypical antipsychotic having the properties of dopamine D2 receptor antagonist. (The product is for research purpose only.)
References
- The effects of S(-) and R(+) sulpiride, metoclopramide, cisapride and domperidone on the small intestine suggest DA2-receptors are involved in the control of small intestinal transit time in rats
- Disposition of enantiomers of sulpiride in humans and rats
- Pharmacotoxicological aspects of levosulpiride (a review)
- Levosulpiride: A review of its clinical use in psychiatry (a review)
- Hydrophilic interaction liquid chromatography-tandem mass spectrometry for the determination of levosulpiride in human plasma
- Spectrophotometric estimation of levosulpiride in bulk drug and formulations
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