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CAS RN: 2624-44-4 | 产品编码: E1145
Etamsylate
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| 产品编码 | E1145 |
| 纯度/分析方法 | >98.0%(T)(HPLC) |
| 分子式/分子量 | C__1__0H__1__7NO__5S = 263.31 |
| 外观与形状（20°C） | 固体 |
| 储存温度 | 室温 (15°C以下阴凉干燥处) |
| 包装和容器 | 1G-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 2624-44-4 |
| 相关CAS RN | 88-46-0 |
| Reaxys-RN | 4166074 |
| PubChem物质ID | 253660744 |
| Merck Index (14) | 3722 |
| MDL编号 | MFCD00867499 |
技术规格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 98.0 % |
| Melting point | 128.0 to 132.0 °C |
物性（参考值）
| 熔点 | 130 °C |
| 水溶性 | 可溶 |
GHS
相关法规
| RTECS# | DB6145000 |
运输信息
| HS编码* | 2921.19-000 |
应用
Ethamsylate: A Platelet Adhesive Agent
Ethamsylate is an inhibitor of prostaglandin biosynthesis. Recent studies have been showed that ethamsylate promotes P-selectin-dependent, platelet adhesive mechanisms. It is used as a synthetic hemostatic agent.
References
- Etamsylate as inhibitor of prostaglandin biosynthesis in pregnant human myometrium in vitro
- Beagle puppy model of intraventricular hemorrhage: ethamsylate studies
- The hemostatic agent ethamsylate enhances P-selectin membrane expression in human platelets and cultured endothelial cells
- Therapeutic efficacy and mechanism of action of ethamsylate, a long-standing hemostatic agent (a review)
- Simultaneous determination of ethamsylate, tramadol and lidocaine in human urine by capillary electrophoresis with electrochemiluminescence detection
- Application of HPLC for the simultaneous determination of ethamsylate and mefenamic acid in bulk drugs and tablets
参考文献
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