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CAS RN: 5116-24-5 | 产品编码: D6190
2'-Deoxy-5-(hydroxymethyl)uridine
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| 产品编码 | D6190 |
| 纯度/分析方法 | >98.0%(T)(HPLC) |
| 分子式/分子量 | C__1__0H__1__4N__2O__6 = 258.23 |
| 外观与形状（20°C） | 固体 |
| 储存温度 | 室温 (15°C以下阴凉干燥处) |
| 储存在惰性气体下 | 存放于惰性气体之中 |
| 应避免的情况 | 空气 |
| CAS RN | 5116-24-5 |
| Reaxys-RN | 31615 |
| MDL编号 | MFCD00047489 |
技术规格
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 98.0 % |
| NMR | confirm to structure |
物性（参考值）
| 熔点 | 179 °C |
GHS
相关法规
| RTECS# | YU7600000 |
运输信息
| HS编码* | 2934.99-000 |
应用
2'-Deoxy-5-(hydroxymethyl)uridine: A Base-Modified 2’-Deoxynucleoside Used in Oxidative Stress and Cancer Studies
2'-Deoxy-5-(hydroxymethyl)uridine is a base-modified 2’-deoxynucleoside with anticancer and antiviral activities.1,2) It also acts as a diagnostic biomarker for oxidative stress in mammalian cells.3,4) Therefore, it has been reported to be used as an indicator of cancer. (The product is for research purpose only.)
References
- 1) Synthesis and biological activities of 5-(hydroxymethyl, azidomethyl, or aminomethyl)-2'-deoxyuridine and related 5'-substituted analogs
- 2) Synergistic enhancement of 5-fluorouracil cytotoxicity by deoxyuridine analogs in cancer cells
- 3) Effect of blueberry ingestion on natural killer cell counts, oxidative stress, and inflammation prior to and after 2.5 h of running
- 4) The Multiple Cellular Roles of SMUG1 in Genome Maintenance and Cancer (a review)
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