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CAS RN: 485-71-2 | 产品编码: C0347
Cinchonidine
技术规格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 90.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Specific rotation [a]20/D | -105 to -110 deg(C=1, EtOH) |
物性（参考值）
| 熔点 | 206 °C |
| 比旋光度 [α]D | -108° (C=1,EtOH) |
| 水溶性 | 不溶 |
| 溶解性（可溶于） | 乙醚, 醇, 氯仿 |
GHS
| 象形图 |
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| 信号词 | Warning |
| 危险性说明 | H302 : Harmful if swallowed. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
相关法规
| RTECS# | GD2975000 |
运输信息
| HS编码* | 2939.20-000 |
应用
Cinchonidine: A Cinchona Alkaloid with both Biological and Asymmetric Catalytic Activity
Cinchona alkaloids (quinine [Q0028], quinidine [Q0006], cinchonidine and cinchonine [C0350]) is isolated from Cinchona plants, and have been used as traditional medicines for the treatment of malaria as well as several diseases.1) Recently studies has revealed that cinchona alkaloids exerts antimalarial, anti-obesity, anti-cancer, anti-oxidant, anti-inflammatory, anti-microbial activity.2) On the other hand, in organic chemistry, cinchona alkaloids have been used as useful catalysts in asymmetric synthesis.3,4) (The product is for research purpose only.)
References
- 1) Quantitative determination of major alkaloids in Cinchona bark by supercritical fluid chromatography
- 2) Spectrum of biological properties of cinchona alkaloids: a brief review
- 3) Asymmetric Mannich Reactions of β-Keto Esters with Acyl Imines Catalyzed by Cinchona Alkaloids
- 4) In situ characterization of the adsorption of cinchona chiral modifiers on platinum surfaces (a review)
参考文献