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CAS RN: 71125-38-7 | Product Number: M1959
Meloxicam
![Meloxicam No-Image](/medias/M1959.jpg?context=bWFzdGVyfHJvb3R8NDg5Nzd8aW1hZ2UvanBlZ3xhR1k0TDJneE5TODRPVEl5TkRrNU1USXhNVGd5TDAweE9UVTVMbXB3Wnd8Y2JhY2YxOTY2ZDFlMDhkZmM5NWNiYTk4YzcwODc4ZGRlZmJkNWM5MTJlOThhMzBiYzQyZWVjNzEzZWFmMjQ4OA)
Purity: >98.0%(HPLC)
Synonyms:
- 4-Hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-2H-1,2-benzothiazine-3-carboxamide 1,1-Dioxide
Product Documents:
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* The storage conditions are subject to change without notice.
* The storage conditions are subject to change without notice.
Product Number | M1959 |
Purity / Analysis Method | >98.0%(HPLC) |
Molecular Formula / Molecular Weight | C__1__4H__1__3N__3O__4S__2 = 351.40 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Refrigerated (0-10°C) |
Condition to Avoid | Heat Sensitive |
CAS RN | 71125-38-7 |
Reaxys Registry Number | 5886369 |
PubChem Substance ID | 87560523 |
Merck Index (14) | 5826 |
MDL Number | MFCD00868752 |
Specifications
Appearance | White to Light yellow to Green powder to crystaline |
Purity(HPLC) | min. 98.0 area% |
Purity(Neutralization titration) | min. 96.0 % |
Properties (reference)
Melting Point | 255 °C |
GHS
Pictogram |
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Signal Word | Danger |
Hazard Statements | H301 : Toxic if swallowed. |
Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
Related Laws:
RTECS# | DL0702000 |
Transport Information:
UN Number | UN2811 |
Class | 6.1 |
Packing Group | III |
H.S.code* | 2935.90-000 |
Application
Meloxicam: A Preferential Cyclooxygenase-2 (COX-2) Inhibitor
Meloxicam is a non-steroidal anti-inflammatory drug (NSAID), and a preferential cyclooxygenase-2 (COX-2) inhibitor. The mechanism of action is mainly by inhibition of the enzyme COX in the arachidonic acid metabolism pathway, resulting in reduced prostaglandin synthesis. In theory, a drug that selectively inhibited COX-2 might block inflammation, pain, and fever produced by prostaglandins while reducing the side effects (gastric erosions and ulcers) associated with inhibition of COX-1. (The product is for research purpose only.)
References
- Meloxican: Influence on arachidonic acid metabolism: Part 1. In vitro findings
- Meloxican: Influence on arachidonic acid metabolism: Part II. In vivo findings
- Evaluation of pharmacological profile of meloxicam as an anti-inflammatory agent, with particular reference to its relative selectivity for cyclooxygenase-2 over cyclooxygenase-1
- Differential inhibition of cyclooxygenases-1 and -2 by meloxicam and its 4’-isomer
- Meloxicam: a reappraisal of pharmacokinetics, efficacy and safety (a review)
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