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CAS RN: 3056-17-5 | Product Number: D3580
2',3'-Didehydro-3'-deoxythymidine
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Purity: >98.0%(T)(HPLC)
Synonyms:
- d4T
- 2',3'-Anhydrothymidine
- 1-(2,3-Dideoxy-β-D-glycero-2-pentenofuranosyl)thymine
- Stavudine
- Sanilvudine
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 1G |
₩111,000
|
2 | 6 | It can be shipped in about 2 weeks after ordering | |
| 5G |
₩353,400
|
15 | 1 | Contact Us |
* Please contact our distributor of SEJIN CI Co., Ltd.
if you would like to purchase TCI products. The above prices do not include freight cost, customs charge and other charges to the destination. SEJIN CI Co., Ltd. (Phone: 02-2655-2480 / email:
sales@sejinci.co.kr)
* The storage conditions are subject to change without notice.
* The storage conditions are subject to change without notice.
Supplemental Product Information:
This product is a sample for RUO (research use only). Do not use this product for any purpose other than testing and research.
| Product Number | D3580 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__0H__1__2N__2O__4 = 224.22 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 3056-17-5 |
| Reaxys Registry Number | 618327 |
| PubChem Substance ID | 87559878 |
| SDBS (AIST Spectral DB) | 52178 |
| MDL Number | MFCD00132921 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 98.0 % |
| Specific rotation [a]20/D | -44.0 to -48.0 deg(C=0.69, H2O) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 166 °C(dec.) |
| Specific Rotation | -46° (C=0.69,H2O) |
| Solubility in water | Soluble |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H373 : May cause damage to organs through prolonged or repeated exposure. H341 : Suspected of causing genetic defects. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P260 : Do not breathe dust/ fume/ gas/ mist/ vapors/ spray. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P405 : Store locked up. |
Related Laws:
| RTECS# | XP2075000 |
Transport Information:
| H.S.code* | 2940.00-000 |
Application
Stavudine: A Nucleoside Reverse Transcriptase Inhibitor
Stavudine is a nucleoside reverse transcriptase inhibitor that active against HIV1. Stavudine is a synthetic nucleoside analogue of the naturally occurring nucleoside thymidine. Intracellularly, stavudine is converted by cellular enzymes to the active metabolite, stavudine-5'-triphosphate. The triphosphate inhibits the activity of viral reverse transcriptase both by competing with the natural substrate, thymidine-5'-triphosphate, and by its incorporation into viral DNA causing termination of viral DNA chain. (The product is for research purpose only.)
References
- Potent and selective in vitro activity of 3'-deoxythymidin-2'-ene (3'-deoxy-2',3'-didehydrothymidine) against human immunodeficiency virus
- Antiretroviral activity of stavudine (2',3'-didehydro-3'-deoxythymidine, D4T) (a review)
- Comparison of metabolism and in vitro antiviral activity of stavudine versus other 2',3'-dideoxynucleoside analogues
Application
Synthesis and Anti-HIV-1 Activities of Novel Podophyllotoxin Derivatives Containing Stavudine
References
PubMed Literature
Articles/Brochures
TCIMAIL
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
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Specifications
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