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CAS RN: 129639-79-8 | Product Number: A3213
Abafungin
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Purity: >95.0%(HPLC)
Synonyms:
- N-[4-[2-(2,4-Dimethylphenoxy)phenyl]-2-thiazolyl]-1,4,5,6-tetrahydro-2-pyrimidinamine
- 4-[2-(2,4-Dimethylphenoxy)phenyl]-N-(1,4,5,6-tetrahydropyrimidin-2-yl)thiazol-2-amine
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 50MG |
₩383,000
|
2 | 1 | Contact Us | |
| 250MG |
₩1,276,500
|
8 | 4 | Contact Us |
* Please contact our distributor of SEJIN CI Co., Ltd.
if you would like to purchase TCI products. The above prices do not include freight cost, customs charge and other charges to the destination. SEJIN CI Co., Ltd. (Phone: 02-2655-2480 / email:
sales@sejinci.co.kr)
* The storage conditions are subject to change without notice.
* The storage conditions are subject to change without notice.
| Product Number | A3213 |
| Purity / Analysis Method | >95.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__1H__2__2N__4OS = 378.49 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 129639-79-8 |
| Reaxys Registry Number | 11337934 |
| PubChem Substance ID | 468590172 |
| MDL Number | MFCD00942263 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Melting point | 197.0 to 201.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 199 °C |
GHS
Related Laws:
Transport Information:
| H.S.code* | 2934.10-000 |
Application
Abafungin: A Thiazole Type Antifungal Agent with a Novel Mechanism of Action
Abafungin is a broad-spectrum thiazole type antifungal agent with a novel mechanism of action. Mode of action studies suggested that inhibits the enzyme sterol-C-24-methyltransferase which catalyzes the transmethylation at the C-24 position of the sterol side chain. In addition, abafungin directly impairs the fungal cell membrane.
References
- Modes of Action of the New Arylguanidine Abafungin beyond Interference with Ergosterol Biosynthesis and in vitro Activity against Medically Important Fungi
- Thiazoles: a valuable insight into the recent advances and biological activities (a review)
- Bioactive thiazole and benzothiazole derivatives (a review)
Articles/Brochures
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Specifications
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