Maintenance Notice (3:30 - 10:00 AM December 21, 2024 UTC): This website is scheduled to be unavailable due to maintenance. We appreciate your patience and understanding.
Published TCIMAIL newest issue No.197 | Notice of Discontinuing the Use of Password-Protected Compressed Files | Product Document Searching Made Easy by 2D Code! | TCI Life Science News December 2024 | [TCIPracticalExample] Reduction of Amide Group Using... | Various analytical charts can be searched on each product detail page and Product Document Search (The kinds of analytical charts differ by product)
Maximum quantity allowed is 999
Please select the quantity
CAS RN: 104-06-3 | Product Number: T3632
Thiacetazone
×
![]()
×
Purity: >98.0%(HPLC)
Synonyms:
- (4-Acetylamino)benzaldehyde Thiosemicarbazone
- N-[4-[(2-Carbamothioylhydrazono)methyl]phenyl]acetamide
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 250MG |
$78.00
|
7 | 0 | It can be shipped in about 2 weeks after ordering |
* Please contact our distributors or
TCI
to order our products. The above prices do not include freight cost, customs, and other charges to the destination.
* The storage conditions are subject to change without notice.
| Product Number | T3632 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__0H__1__2N__4OS = 236.29 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container | 250MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 104-06-3 |
| Reaxys Registry Number | 2810335 |
| PubChem Substance ID | 354335296 |
| MDL Number | MFCD00022157 |
Specifications
| Appearance | White to Orange to Green powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Elemental analysis(Nitrogen) | 22.50 to 24.50 % |
Properties (reference)
| Melting Point | 223 °C |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
Related Laws:
| RTECS# | AE3850000 |
Transport Information:
| H.S.code* | 2930.90-900 |
Application
Thiacetazone: A Bacteriostatic Antitubercular Agent
Thiacetazone has been used as an antitubercular agent since the 1960s. Reportedly, thiacetazone is a prodrug that is oxidatively converted to their active forms by the flavin monooxygenase EtaA of Mycobacterium tuberculosis. Thiacetazone is bacteriostatic in action against tuberculosis through the inhibition of mycolic acid biosynthesis. Because the activity of thiacetazone is weak, it is usually used as a combination with first-line tuberculosis medications, such as isoniazid [I0138] and rifampicin [R0079]. (The product is for research purpose only.)
References
- Oxidative Activation of Thiacetazone by the Mycobacterium tuberculosis Flavin Monooxygenase EtaA and Human FMO1 and FMO3
- A common mechanism of inhibition of the Mycobacterium tuberculosis mycolic acid biosynthetic pathway by isoxyl and thiacetazone
- Bioactivation of antituberculosis thioamide and thiourea prodrugs by bacterial and mammalian flavin monooxygenases (a review)
- Antituberculosis agents (a review)
- Isocratic high-performance liquid chromatographic determination of thiacetazone by direct injection of plasma into an internal surface reversed-phase column
PubMed Literature
Articles/Brochures
TCIMAIL
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.