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CAS RN: 123447-62-1 | Product Number: P2058
Prulifloxacin
Purity: >98.0%(T)(HPLC)
Synonyms:
Product Documents:
Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time | Shipping Information |
---|---|---|---|---|---|
1G |
A$333.00
|
4 | 0 | It can be shipped in about 2 weeks after ordering | |
5G |
A$957.00
|
6 | 3 | Contact Us |
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Product Number | P2058 |
Purity / Analysis Method | >98.0%(T)(HPLC) |
Molecular Formula / Molecular Weight | C__2__1H__2__0FN__3O__6S = 461.46 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Frozen (<0°C) |
Condition to Avoid | Light Sensitive,Heat Sensitive |
Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image) |
CAS RN | 123447-62-1 |
Reaxys Registry Number | 5894071 |
PubChem Substance ID | 253660145 |
Merck Index (14) | 7908 |
MDL Number | MFCD00864847 |
Specifications
Appearance | Light orange to Yellow to Green powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Purity(Nonaqueous Titration) | min. 98.0 % |
Properties (reference)
Melting Point | 220 °C(dec.) |
Maximum Absorption Wavelength | 276(H2O) nm |
Solubility in water | Insoluble |
Solubility (soluble in) | Dimethylformamide |
Solubility (insoluble in) | Ether |
GHS
Related Laws:
RTECS# | XJ0600000 |
Transport Information:
H.S.code* | 2941.90-000 |
Application
A Broad-Spectrum Fluoroquinolone Antibacterial Agent, Prulifloxacin
Prulifloxacin (PUFX), the prodrug of ulifloxacin (NM394), is a broad-spectrum fluoroquinolone antibacterial agent. After absorption, prulifloxacin is metabolized by esterases to ulifloxacin. Ulifloxacin, the active form of prulifloxacin, is generally more active than other fluoroquinolones against a variety of Gram-positive and Gram-negative bacteria including Pseudomonas aeruginosa.
References
- Prulifloxacin
- Pharmacologic characteristics of prulifloxacin
- Polyamidoamine (PAMAM) dendrimers as biocompatible carriers of quinolone antimicrobials: An in vitro study
- Paraoxonase has a major role in the hydrolysis of prulifloxacin (NM441), a prodrug of a new antibacterial agent
- K. Tougou, A. Nakamura, S. Watanabe, Y. Okuyama, A. Morino, Drug Metab. Dispos. 1998, 26, 355.
- Comparative assessment of prulifloxacin, sparfloxacin, gatifloxacin and levofloxacin in the rabbit model of proarrhythmia
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