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CAS RN: 518-28-5 | Product Number: P1771

Podophyllotoxin


Purity: >95.0%(HPLC)
Synonyms:
Product Documents:
1G
A$93.00
10   0   It can be shipped in about 2 weeks after ordering
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Product Number P1771
Purity / Analysis Method >95.0%(HPLC)
Molecular Formula / Molecular Weight C__2__2H__2__2O__8 = 414.41 
Physical State (20 deg.C) Solid
Storage Temperature Refrigerated (0-10°C)
Condition to Avoid Heat Sensitive
Packaging and Container 1G-Glass Bottle with Plastic Insert (View image)
CAS RN 518-28-5
Reaxys Registry Number 99163
PubChem Substance ID 468592573
Merck Index (14) 7546
MDL Number

MFCD00075290

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 95.0 area%
Melting point 177.0 to 185.0 °C
Specific rotation [a]20/D -125 to -133 deg(C=1, CHCL3)
Properties (reference)
Melting Point 181 °C
Specific Rotation -129° (C=1,CHCl3)
Maximum Absorption Wavelength 292(MeOH) nm
GHS
Pictogram Pictogram
Signal Word Danger
Hazard Statements H310 : Fatal in contact with skin.
H301 : Toxic if swallowed.
H315 : Causes skin irritation.
H319 : Causes serious eye irritation.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P270 : Do not eat, drink or smoke when using this product.
P262 : Do not get in eyes, on skin, or on clothing.
P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P337 + P313 : If eye irritation persists: Get medical advice/ attention.
P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P361 + P364 : Take off immediately all contaminated clothing and wash it before reuse.
P332 + P313 : If skin irritation occurs: Get medical advice/ attention.
P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth.
P302 + P352 + P310 : IF ON SKIN: Wash with plenty of water. Immediately call a POISON CENTER/doctor.
P405 : Store locked up.
Related Laws:
RTECS# LV2500000
Transport Information:
UN Number UN2811
Class 6.1
Packing Group II
H.S.code* 3002.90-000
*This code is applied to the products when TCI exports from Japan and not for import in your country.
Application
Podophyllotoxin: A Lignin with Antineoplastic and Antiviral Properties

Podophyllotoxin is a naturally occurring lignan isolated from Podophyllum peltatum, with important antineoplastic and antiviral properties. Although the exact mechanism of action is unknown, podophyllotoxin is believed to exert its antimitotic effect by binding to tubulin. In addition, podophyllotoxin derivatives, such as etoposide [E0675] and teniposide [T3109], act as topoisomerase II inhibitors and can cause arrest in the cell cycle of tumor at the G2/M stage. (The product is for research purpose only.)

References


TCIMAIL
Product Documents (Note: Some products will not have analytical charts available.)
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