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CAS RN: 93957-55-2 | Product Number: F0820
Fluvastatin Sodium Salt
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Purity: >98.0%(HPLC)(N)
Synonyms:
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days |
|---|---|---|---|
| 1G |
A$312.00
|
Contact Us | 6 |
| 5G |
A$904.00
|
9 | 1 |
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* ChemSupply Australia Pty Ltd (Phone: 08-8440-2000 / email: sales@chemsupply.com.au)
Supplemental Product Information:
Previously this product had been labeled as a hydrate form both in product name and molecular formula. The hydrate form had no exclusive CAS RN and used to share the same CAS RN as the anhydrous form.
To avoid any misleading information and since moisture in product is considered as an impurity, we have decided to remove the term 'Hydrate' from product name and 'xH2O' from the molecular formula for such products.
Please use it at ease since there is no difference in product quality, even if you see the previous indications on a part of label.
| Product Number | F0820 |
| Purity / Analysis Method | >98.0%(HPLC)(N) |
| Molecular Formula / Molecular Weight | C__2__4H__2__5FNNaO__4 = 433.46 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 93957-55-2 |
| Related CAS RN | 93957-54-1 |
| PubChem Substance ID | 160870917 |
| Merck Index (14) | 4218 |
| MDL Number | MFCD00929076 |
Specifications
| Appearance | Light orange to Yellow to Green powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(with Total Nitrogen) | min. 98.0 %(calcd.on anh.substance) |
| Water | max. 6.0 % |
Properties (reference)
| Solubility (soluble in) | Methanol |
GHS
Related Laws:
| RTECS# | MJ9675100 |
Transport Information:
| H.S.code* | 2933.99-000 |
Application
Fluvastatin Sodium Salt: A HMG-CoA Reductase Inhibitor with Anti-Oxidative Properties
Enzyme HMG-CoA (3-hydroxy-3-methylglutaryl coenzyme A) reductase catalyzes the rate-limiting step in cholesterol biosynthesis. Statins inhibit the action of HMG-CoA reductase resulting in the reduction of low-density-lipoprotein (LDL) and total cholesterol levels. In addition, statins (in particular fluvastatin) have reported their anti-oxidative properties. Many statins are metabolized by cytochrome P450 3A4 (CYP3A4) while fluvastatin is metabolized by CYP2C9. (The product is for research purpose only.)
References
- Inhibition of cholesterol synthesis ex vivo and in vivo by fluvastatin, a new inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase
- Structural mechanism for statin inhibition of HMG-CoA reductase
- Anti-oxidative properties of fluvastatin, an HMG-CoA reductase inhibitor, contribute to prevention of atherosclerosis in cholesterol-fed rabbits
- In vitro comparative inhibition profiles of major human drug metabolizing cytochrome P450 isoenzymes (CYP2C9, CYP2D6 and CYP3A4) by HMG-CoA reductase inhibitors
- The 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor fluvastatin: effect on human cytochrome P-450 and implications for metabolic drug interactions
PubMed Literature
Articles/Brochures
TCIMAIL
[TCIMAIL No.154] HMG-CoA Reductase Inhibitors (Statins)[Research Articles] Ni/Cu-Catalyzed Defluoroborylation of Fluoroarenes
Product Documents (Note: Some products will not have analytical charts available.)
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Specifications
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