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CAS RN: 3416-05-5 | Product Number: D6100
3'-Deoxythymidine
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Purity: >98.0%(T)(HPLC)
Synonyms:
- 2',3'-Dideoxythymidine
- DDT
- 1-[(2R,5S)-5-(Hydroxymethyl)tetrahydrofuran-2-yl]-5-methylpyrimidine-2,4(1H,3H)-dione
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 250MG |
A$342.00
|
25 | 0 | Contact Us |
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* ChemSupply Australia Pty Ltd (Phone: 08-8440-2000 / email: sales@chemsupply.com.au)
| Product Number | D6100 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__0H__1__4N__2O__4 = 226.23 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive |
| Packaging and Container | 250MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 3416-05-5 |
| Reaxys Registry Number | 21884 |
| MDL Number | MFCD00010570 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 98.0 % |
| Melting point | 152.0 to 156.0 °C |
| Specific rotation | +14.0 to +18.0 deg(C=0.6, water) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 154 °C |
GHS
Related Laws:
Transport Information:
| H.S.code* | 2934.99-000 |
Application
3'-Deoxythymidine: A Thymidine Analog with Antiviral Activity
3'-Deoxythymidine (2',3'-dideoxythymidine) is a thymidine analog that has antiviral activity. There are reports that it inhibits HIV replication in vitro. (The product is for research purpose only.)
References
- Both 2',3'- dideoxythymidine and its 2',3'-unsaturated derivative (2',3'-dideoxythymidinene) are potent and selective inhibitors of human immunodeficiency virus replication in vitro
- Synergistic inhibition of human immunodeficiency virus type 1 replication in vitro by two-drug and three-drug combinations of 3'-azido-3'-deoxythymidine, phosphonoformate, and 2',3'-dideoxythymidine
- Synthesis, anti-HIV activity, and resistance profile of thymidine phosphonomethoxy nucleosides and their bis-isopropyloxymethylcarbonyl (bisPOC) prodrugs
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