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CAS RN: 14919-77-8 | Product Number: B4108
Benserazide Hydrochloride
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Purity: >97.0%(T)(HPLC)
Synonyms:
- DL-Serine 2-(2,3,4-Trihydroxybenzyl)hydrazide Hydrochloride
Product Documents:
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Product Number | B4108 |
Purity / Analysis Method | >97.0%(T)(HPLC) |
Molecular Formula / Molecular Weight | C__1__0H__1__5N__3O__5·HCl = 293.70 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
Store Under Inert Gas | Store under inert gas |
Condition to Avoid | Light Sensitive,Hygroscopic |
Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image) |
CAS RN | 14919-77-8 |
Related CAS RN | 322-35-0 |
Reaxys Registry Number | 6494463 |
PubChem Substance ID | 253659990 |
Merck Index (14) | 1050 |
MDL Number | MFCD00078571 |
Specifications
Appearance | White to Light yellow to Light orange powder to crystal |
Purity(HPLC) | min. 97.0 area% |
Purity(Nonaqueous Titration) | min. 97.0 % |
Properties (reference)
Melting Point | 180 °C(dec.) |
Maximum Absorption Wavelength | 272(HCl aq.) nm |
Solubility in water | Soluble |
GHS
Pictogram |
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Signal Word | Warning |
Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
RTECS# | VT9632300 |
Transport Information:
H.S.code* | 2928.00-000 |
Application
Benserazide: An Aromatic L-Amino Acid Decarboxylase or L-DOPA Decarboxylase Inhibitor
Benserazide is an aromatic L-amino acid decarboxylase or L-DOPA [D0600] decarboxylase inhibitor, which is unable to cross the blood–brain barrier.
References
- Antiparkinsonian effect of a new selective adenosine A2A receptor antagonist in MPTP-treated monkeys
- Simultaneous determination of levodopa and benserazide by stopped-flow injection analysis and three-way multivariate calibration of kinetic-spectrophotometric data
- Dopamine D1 and D2 receptor contributions to L-DOPA-induced dyskinesia in the dopamine-depleted rat
- The 3-hydroxy-3-methylglutaryl-CoA reductase inhibitor lovastatin reduces severity of L-DOPA-induced abnormal involuntary movements in experimental Parkinson's disease
- In-vitro and in-vivo inhibition by benserazide of clorgyline-resistant amine oxidases in rat cardiovascular tissues
PubMed Literature
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