In photoproximity labeling, short-lived reactive active species probes are generated by light irradiation. These probes diffuse through the solution and covalently bind to nearby biomolecules, thus imparting a tag. For instance, it has been reported that antibodies covalently linked to photoreactive catalysts can label the microenvironment surrounding antibody-bound proteins through activation of probes. This technique does not necessitate the use of genetic modification technology. We offer products with different labeling radii for proximity labeling.

The Mitochondrial Isolation Kit [M3527] can be used to easily isolate mitochondria from cultured mammalian cells and tissue. Isolated mitochondria can be used for downstream analyses such as Western blotting. Please take a look at the application examples in the brochure.

Pre-divided products save the step of weighing. Biotinylation reagents, click reaction reagents, fluorescent labeling reagents, crosslinkers are available.

The GRFT (Griffithsin), which is derived from red algae, is expected for practical use as an antiviral lectin (glycan-binding protein) against pathogenic viruses like HIV. Recently, it has been reported that GRFT exhibits various types of antiviral effects against SARS-CoV-2. The recombinant GRFT is available in large quantities.

TCI provides high purity reagents to meet the demands of cutting-edge scientific research. With TCI, researchers get reliable quality at a reasonable price. TCI offers more than 30,000 high quality chemical products within specifications and stability to safeguard your scientific research.

Choose TCI – a worthy investment for your research!

Released in March 2024, TCI's latest issue features Prof. Hiroshi Shinokubo and coworkers’ article “Development of typical-element-doped functional π-systems consisting of 
naphthalene monoimide units” and Teacher Hiroyuki Onuki's chemistry chat “Difficulties in Senior High School Chemistry Experiments”.

We also feature research on:

• SpiroBpy-BPin: Ligand for meta-Selective Catalytic C-H Borylation
• Anti-Non-human Glycoform Antibodies for Flow Cytometry
• Xanthine Oxidase Inhibitor - Febuxostat
• OCT4 Activators