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Stilbene Ligand for Stereospecific Cross-Coupling Reactions

Stilbene Ligand for Stereospecific Cross-Coupling Reactions

Advantages

  • Commercialized by the introduction of technology from ENEOS.
  • Enables stereospecific cross-coupling reactions between tertiary alkyl pivalates and aryl boronic acids in the presence of a nickel catalyst.
  • Enables the construction of quaternary chiral carbons.
  • Useful for the synthetic research of pharmaceutical intermediates.

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Application: Stereospecific cross-coupling reaction 1)

Stereospecific cross-coupling reaction using E1539 as a catalytic ligand

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Related Product Category

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Reference

  1. 1) Overcoming the Naphthyl Requirement in Stereospecific Cross-Couplings to Form Quaternary Stereocenters

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