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CAS RN: 69388-84-7 | Product Number: U0159
Sulbactam Sodium
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Purity: >98.0%(T)(HPLC)
Synonyms:
- Sodium (2S,5R)-3,3-Dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4,4-Dioxide
Product Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
|---|---|---|---|---|---|
| 1G |
$149.00
|
Contact Us | Contact Us | 23 |
|
| 5G |
$446.00
|
1 | Contact Us | 23 |
|
* Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact TCI for lead times on items not in stock. Excludes regulated items and items that ship on ice.
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| Product Number | U0159 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__8H__1__0NNaO__5S = 255.22 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Heat Sensitive |
| CAS RN | 69388-84-7 |
| Reaxys Registry Number | 3599871 |
| MDL Number | MFCD01750374 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Specific rotation | +219 to +233 deg(C-1, water) |
| Water | max. 1.0 % |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 190 °C |
GHS
Related Laws:
| RTECS# | XH9220000 |
Transport Information:
| HS Number | 2941.90.5000 |
Application
Sulbactam Sodium: A β-Lactamase Inhibitor Used with Another Antibiotic
Sulbactam [S0868] and its sodium salt are β-lactamase inhibitors which are chemically synthesized from 6-APA [A0800]. Although they have low antimicrobial activity, they inhibit enzymes (β-lactamases) which are produced by bacteria to degrade β-lactam antibiotics such as penicillins and cephalosporins. They are often used in combination with amoxicillin [A2099] or cefoperazone [C2768] to increase the antibiotic spectrum of theirs. (The product is for research purpose only.)
References
- Comparative activities of clavulanic acid, sulbactam, and tazobactam against clinically important β-lactamases
- A Structure-Based Analysis of the Inhibition of Class A β-Lactamases by Sulbactam
- Inhibitor-resistant TEM β-lactamases: phenotypic, genetic and biochemical characteristics (a review)
- Understanding the longevity of the β-lactam antibiotics and of antibiotic/β-lactamase inhibitor combinations (a review)
- Current challenges in antimicrobial chemotherapy: focus on β-lactamase inhibition (a review)
Product Documents (Note: Some products will not have analytical charts available.)
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Specifications
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