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CAS RN: 75438-57-2 | Product Number: M2660
Moxonidine
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Purity: >98.0%(T)
Synonyms:
- 4-Chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-6-methoxy-2-methyl-5-pyrimidinamine
Product Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
|---|---|---|---|---|---|
| 200MG |
$117.00
|
1 | 1 | 1 |
|
| 1G |
$406.00
|
2 | Contact Us | 9 |
|
* Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact TCI for lead times on items not in stock. Excludes regulated items and items that ship on ice.
* To send your quote request for bulk quantities, please click on the "Request Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | M2660 |
| Purity / Analysis Method | >98.0%(T) |
| Molecular Formula / Molecular Weight | C__9H__1__2ClN__5O = 241.68 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 75438-57-2 |
| Reaxys Registry Number | 6769959 |
| PubChem Substance ID | 253662597 |
| Merck Index (14) | 6293 |
| MDL Number | MFCD00865794 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 97.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
Properties (reference)
| Melting Point | 206 °C |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H301 : Toxic if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
Related Laws:
| RTECS# | UV6260290 |
Transport Information:
| UN Number (DOT-AIR) | UN2811 |
| Class (DOT-AIR) | 6.1 |
| Packing Group (TCI-A) | III |
| HS Number | 2933.99.5300 |
Application
選択的イミダゾリンl1受容体アゴニストでありα2-アドレナリン受容体アゴニストでもあるモキソニジン
Moxonidine is an imidazoline compound with selective agonist activity at imidazoline I1 receptors and only minor activity at α2-adrenoceptors. It is used for the treatment of hypertension as a centrally acting antihypertensive. (The product is for research purpose only.)
References
- Moxonidine, a centrally acting antihypertensive agent, is a selective ligand for I1-imidazoline sites
- Moxonidine, a selective α2-adrenergic and imidazoline receptor agonist, produces spinal antinociception in mice
- Moxonidine, a selective imidazoline/α2 adrenergic receptor agonist, synergizes with morphine and deltorphin II to inhibit substance P-induced behavior in mice
- Central imidazoline (I1) receptors as targets of centrally acting antihypertensives: moxonidine and rilmenidine (a review)
- Moxonidine: a review of its use in essential hypertension
PubMed Literature
Articles/Brochures
TCIMAIL
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Safety Data Sheet (SDS)
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Specifications
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