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CAS RN: 43229-80-7 | Product Number: F0881
Formoterol Fumarate
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Purity:
Synonyms:
Product Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
|---|---|---|---|---|---|
| 10MG |
$129.00
|
4 | Contact Us | 24 |
|
| 50MG |
$386.00
|
1 | 1 | 22 |
|
* Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact TCI for lead times on items not in stock. Excludes regulated items and items that ship on ice.
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*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
Supplemental Product Information:
Previously this product had been labeled as a hydrate form both in product name and molecular formula. The hydrate form had no exclusive CAS RN and used to share the same CAS RN as the anhydrous form.
To avoid any misleading information and since moisture in product is considered as an impurity, we have decided to remove the term 'Hydrate' from product name and 'xH2O' from the molecular formula for such products.
Please use it at ease since there is no difference in product quality, even if you see the previous indications on a part of label.
| Product Number | F0881 |
| Molecular Formula / Molecular Weight | C__1__9H__2__4N__2O__4·^^1/__2C__4H__4O__4 = 402.45 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Frozen (<0°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 43229-80-7 |
| Reaxys Registry Number | 8665977 |
| PubChem Substance ID | 253661050 |
| Merck Index (14) | 4245 |
| MDL Number | MFCD03093863 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 97.0 % (total of 2peaks) |
| Purity(Nonaqueous Titration) | min. 98.0 %(calcd.on anh.substance) |
| Water | 1.5 to 5.5 % |
Properties (reference)
| Maximum Absorption Wavelength | 284 nm |
| Solubility in water | Insoluble |
| Solubility (soluble in) | Methanol |
| Solubility (insoluble in) | Ethanol, Ether |
GHS
Related Laws:
| RTECS# | LQ2988000 |
Transport Information:
| HS Number | 2924.29.7790 |
Application
Formoterol Fumarate: A Long-Acting and Selective β2-Adrenoceptor Agonist (LABA)
Formoterol fumarate is a long-acting and selective β2-adrenoceptor agonist (LABA) such as indacaterol maleate [I0927], causing bronchodilation by relaxing the smooth muscle in the airway. Formoterol has more potent activity than short acting β2-adrenoceptor agonist, such as salbutamol [S0531]. Combination inhalers containing formoterol fumarate and a corticosteroid (eg. budesonide [B3909], beclometasone dipropionate [B4464], fluticasone propionate [F0525] or mometasone furoate [M2354]) are often used for the treatment of chronic obstructive pulmonary disease (COPD) and asthma. (The product is for research purpose only.)
References
- Formoterol: pharmacology, molecular basis of agonism, and mechanism of long duration of a highly potent and selective β2-adrenoceptor agonist bronchodilator (a review)
- Formoterol: an update of its pharmacological properties and therapeutic efficacy in the management of asthma (a review)
- Why are long-acting beta-adrenoceptor agonists long-acting?
- Pharmacological basis for duration of effect: formoterol and salmeterol versus short-acting β2-adrenoceptor agonists (a review)
- Effects of formoterol and budesonide on GM-CSF and IL-8 secretion by triggered human bronchial epithelial cells
- Chiral HPLC analysis of formoterol stereoisomers and thermodynamic study of their interconversion in aqueous pharmaceutical formulations
PubMed Literature
Articles/Brochures
TCIMAIL
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Safety Data Sheet (SDS)
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Specifications
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