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CAS RN: 103639-04-9 | Product Number: O0407
Ondansetron Hydrochloride Dihydrate
Purity: >98.0%(T)(HPLC)
Synonyms:
- 1,2,3,9-Tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-4H-carbazol-4-one Hydrochloride Dihydrate
Product Documents:
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Product Number | O0407 |
Purity / Analysis Method | >98.0%(T)(HPLC) |
Molecular Formula / Molecular Weight | C__1__8H__1__9N__3O·HCl·2H__2O = 365.86 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Refrigerated (0-10°C) |
Condition to Avoid | Heat Sensitive |
Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image) |
CAS RN | 103639-04-9 |
Related CAS RN | 99614-02-5&99614-01-4 |
Reaxys Registry Number | 7403248 |
PubChem Substance ID | 172089079 |
MDL Number | MFCD00374371 |
Specifications
Appearance | White to Almost white powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Purity(Nonaqueous Titration) | min. 98.0 % |
Melting point | 175.0 to 179.0 °C |
Properties (reference)
Melting Point | 178 °C |
GHS
Pictogram | |
Signal Word | Danger |
Hazard Statements | H301 : Toxic if swallowed. |
Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
Related Laws:
RTECS# | FE6375500 |
Transport Information:
UN Number | UN2811 |
Class | 6.1 |
Packing Group | III |
H.S.code* | 2933.29-000 |
Application
5-HT3 Receptor Antagonist
References
- The 5-HT3B subunit is a major determinant of serotonin-receptor function
- P. A. Davies, M. Pistis, M. C. Hanna, J. A. Peters, J. J. Lambert, T. G. Hales, E. F. Kirkness, Nature 1999, 397, 359.
- Pharmacological properties of GR38032F, a novel antagonist at 5-HT3 receptors
- The effects of ondansetron (GR38032F) in rats and mice treated subchronically with diazepam
- Antidepressant-like effects of serotonin type-3 antagonist, ondansetron: an investigation in behaviour-based rodent models
- Ondansetron: A review of its pharmacology and preliminary clinical findings in novel applications
- M. I. Wilde, A. Markham, Drugs 1996, 52, 773.
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