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CAS RN: 66852-54-8 | Product Number: H1457
Halobetasol Propionate
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Purity: >98.0%(HPLC)
Synonyms:
- 21-Chloro-6α,9α-difluoro-11β,17α-dihydroxy-16β-methyl-1,4-pregnadiene-3,20-dione 17-Propionate
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 25MG |
$41.00
|
20 | 0 | It can be shipped in about 3-4 weeks after ordering | |
| 100MG |
$125.00
|
3 | 12 | It can be shipped in about 3-4 weeks after ordering |
* Please contact our distributors or
TCI
to order our products. The above prices do not include freight cost, customs, and other charges to the destination.
* The storage conditions are subject to change without notice.
| Product Number | H1457 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__5H__3__1ClF__2O__5 = 484.96 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container | 25MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 66852-54-8 |
| Reaxys Registry Number | 11109992 |
| MDL Number | MFCD00866013 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Specific rotation [a]20/D | +89.0 to +93.0 deg(C=1, Dioxane) |
Properties (reference)
| Melting Point | 221 °C |
| Specific Rotation | 91° (C=1,Dioxane) |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
| RTECS# | TU3723500 |
Transport Information:
| H.S.code* | 2937.22-000 |
Application
Halobetasol propionate: A Super-Potent Corticosteroid
Halobetasol propionate is a super-potent corticosteroid with additional fluorine at the 6α position when compared with clobetasol 17-propionate [C2612]. The additional fluorine in the 6α position further increases its topical anti-inflammatory and antiproliferative activities. In addition, an ointment formulation in combination of halobetasol propionate and fusidic acid [F1007] for treatment of dermal conditions have been reported. (The product is for research purpose only.)
References
- Halobetasol versus clobetasol: A study of potency
- A degradation product of halobetasol propionate-characterization and structure
- Formulation and evaluation of novel combined halobetasol propionate and fusidic acid ointment
- Spectrophotometric determination of clobetasol propionate, halobetasol propionate, quinagolide hydrochloride, through charge transfer complexation
- Screening for corticosteroids in topical pharmaceuticals by HPLC with a scanning ultraviolet detector
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