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CAS RN: 260779-88-2 | Product Number: C3861
Cisapride Monohydrate
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Purity: >98.0%(T)(HPLC)
Synonyms:
- cis-4-Amino-5-chloro-N-[1-[3-(4-fluorophenoxy)propyl]-3-methoxy-4-piperidinyl]-2-methoxybenzamide Monohydrate
- rel-4-Amino-5-chloro-N-[(3S,4R)-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-yl]-2-methoxybenzamide Monohydrate
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
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| 1G |
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| Product Number | C3861 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__2__3H__2__9ClFN__3O__4·H__2O = 483.97 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Hygroscopic |
| Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 260779-88-2 |
| Related CAS RN | 81098-60-4 |
| Reaxys Registry Number | 24940912 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Water | 3.4 to 4.0 % |
| Specific rotation | -1.0 to +1.0 deg(C=1, CHCl3) |
| NMR | confirm to structure |
Properties (reference)
GHS
Related Laws:
Transport Information:
| H.S.code* | 2933.39-000 |
Application
Cisapride: A 5-HT4 Receptor Agonist
Cisapride is a 5-HT4 receptor agonist developed as a gastrointestinal prokinetic agent for the treatment of functional bowel disorders. Cisapride has been reported to be associated with acquired long QT syndrome and ventricular arrhythmias. (The product is for research purpose only.)
References
- Cisapride. An updated review of its pharmacology and therapeutic efficacy as a prokinetic agent in gastrointestinal motility disorders.
- 5-HT4 receptor agonists: similar but not the same (a review)
- Discovery and SAR of N-(1-((substituted piperidin-4-yl)methyl)-3-methoxypiperidin-4-yl)-2-methoxybenzamide derivatives: 5-Hydroxytryptamine receptor 4 agonist as a potent prokinetic agent
Product Documents (Note: Some products will not have analytical charts available.)
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