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CAS RN: 100361-18-0 | Product Number: C2650
7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic Acid
Purity: >98.0%(T)(HPLC)
Synonyms:
Product Documents:
Size | Unit Price | Same Day | 2-3 Business Days |
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1G |
$27.00
|
10 | Contact Us |
5G |
$86.00
|
4 | 1 |
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Product Number | C2650 |
Purity / Analysis Method | >98.0%(T)(HPLC) |
Molecular Formula / Molecular Weight | C__1__2H__8ClFN__2O__3 = 282.66 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
CAS RN | 100361-18-0 |
Reaxys Registry Number | 4264924 |
PubChem Substance ID | 354333349 |
MDL Number | MFCD08458865 |
Specifications
Appearance | White to Almost white powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Purity(Neutralization titration) | min. 98.0 % |
Melting point | 222.0 to 226.0 °C |
Properties (reference)
Melting Point | 224 °C |
GHS
Related Laws:
Transport Information:
H.S.code* | 2933.99-000 |
Application
Synthesis of 1-Cyclopropyl-1,8-naphthyridine Fluoroquinolone Antibacterials and Evaluations of their Antibacterial Activity
C2650 is an important intermediate for preparation of 1-cyclopropyl-1,8-naphthyridine fluoroquinolone antibacterials.
References
- Quinolone antibacterial agents. Synthesis and structure-activity relationships of 8-substituted quinoline-3-carboxylic acids and 1,8-naphthyridine-3-carboxylic acids
- Quinolone antibacterial agents. Synthesis and structure-activity relationships of a series of amino acid prodrugs of racemic and chiral 7-(3-amino-1-pyrrolidinyl)quinolones. Highly soluble quinolone prodrugs with in vivo pseudomonasactivity
- Novel Fluoroquinolone Antibacterial Agents Containing Oxime-Substituted (Aminomethyl)pyrrolidines: Synthesis and Antibacterial Activity of 7-(4-(Aminomethyl)-3-(methoxyimino)pyrrolidin-1-yl)-1-cyclopropyl -6-fluoro -4-oxo-1,4-dihydro[1,8]naphthyridine-3-carboxylic Acid (LB20304)
- Syntheses and biological evaluation of new fluoroquinolone antibacterials containing chiral oximinopyrrolidinea
- Synthesis and antibacteriala activity of novel fluoroquinolones containing substituted piperidines
- 4-Substituted 4-(1H-1,2,3-triazol-1-yl)piperidine: Novel C7 moieties of fluoroquinolones as antibacterial agents
PubMed Literature
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