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CAS RN: 155206-00-1 | Product Number: B6165
Bimatoprost
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Purity: >98.0%(HPLC)
Synonyms:
- (Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(S,E)-3-hydroxy-5-phenylpent-1-en-1-yl]cyclopentyl]-N-ethylhept-5-enamide
- 17-Phenyltrinor-PGF2α Ethylamide
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 5MG |
$207.00
|
3 | 22 | Contact Us | |
| 25MG |
$746.00
|
14 | 17 | Contact Us |
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to order our products. The above prices do not include freight cost, customs, and other charges to the destination.
* The storage conditions are subject to change without notice.
| Product Number | B6165 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__5H__3__7NO__4 = 415.57 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Frozen (-20°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Heat Sensitive |
| CAS RN | 155206-00-1 |
| Reaxys Registry Number | 9365461 |
| PubChem Substance ID | 468590953 |
| Merck Index (14) | 1221 |
| MDL Number | MFCD03411999 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Melting point | 72.0 to 76.0 °C |
| Specific rotation [a]20/D | +34.2 to +37.8 deg(C=1, MeOH) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 75 °C |
| Specific Rotation | 35° (C=1,MeOH) |
| Solubility (soluble in) | Methanol, Ethanol |
| Solubility (slightly sol. in) | Dimethylformamide |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H361 : Suspected of damaging fertility or the unborn child. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P405 : Store locked up. |
Related Laws:
| RTECS# | MJ8808000 |
Transport Information:
| H.S.code* | 2937.50-000 |
Application
Bimatoprost: A Synthetic Prostaglandin F2α (PGF2α) Analog with Unique Ocular Hypotensive Activity
Bimatoprost (AGN 192024) is a synthetic prostaglandin F2α (PGF2α) analog having pharmacological and biochemical properties district from PGF2α. PGF2α is formed from the endocannabinoid anandamide by a biosynthetic pathway involving cyclooxygenase-2 (COX-2). However, bimatoprost selectively mimics the effects of naturally occurring substances, prostamides. The target receptor for bimatoprost and the prostamides appears unique and unrelated to PG- and endocannabinoid-sensitive receptors. Although its mechanism of action is not completely understood, bimatoprost is believed to lower intraocular pressure (IOP) in humans by increasing outflow aqueous humor through both the trabecular meshwork and uveoscleral routes. In clinical, bimatoprost is used for the treatment of glaucoma. (The product is for research purpose only.)
References
- Pharmacological characterization of a novel antiglaucoma agent, bimatoprost (AGN 192024)
- Bimatoprost: A novel antiglaucoma agent (a review)
Product Documents (Note: Some products will not have analytical charts available.)
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