text.skipToContent text.skipToNavigation

Maximum quantity allowed is 999

Please select the quantity

CAS RN: 57149-07-2 | Product Number: N0832

Naftopidil


Purity: >98.0%(T)(HPLC)
Synonyms:
  • 1-[4-(2-Methoxyphenyl)piperazinyl]-3-(1-naphthyloxy)propan-2-ol
Product Documents:
5G
$50.00
1   1   ≥100 

* Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact TCI for lead times on items not in stock. Excludes regulated items and items that ship on ice.
* To send your quote request for bulk quantities, please click on the "Request Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.


Product Number N0832
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__2__4H__2__8N__2O__3 = 392.50 
Physical State (20 deg.C) Solid
Storage Temperature Room Temperature (Recommended in a cool and dark place, <15°C)
CAS RN 57149-07-2
Reaxys Registry Number 629965
PubChem Substance ID 87560652
SDBS (AIST Spectral DB) 52403
Merck Index (14) 6356
MDL Number

MFCD00242741

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 98.0 %
Melting point 125.0 to 129.0 °C
Properties (reference)
Melting Point 127 °C
Solubility in water Insoluble
GHS
Related Laws:
RTECS# TL9336500
Transport Information:
HS Number 2933.59.8000
Application
α1アドレナリン受容体のα1D とα1Aサブタイプ選択的アンタゴニスト,ナフトピジル

Naftopidil is an α1D and α1A subtype-selective α1-adrenoceptor antagonist. The α1-adrenergic receptor is a G protein-coupled receptor (GPCR) associated with the Gq heterotrimeric G-protein. The receptor consists of three subtypes, including α1A-, α1B-, and α1D-adrenergic. Naftopidil is subtype-selective for the α1D-adrenoceptor with approximately 3- and 17-fold higher affinity than for the α1A- and α1B-adrenoceptor subtypes, respectively. In Japan, naftopidil is used to treat lower urinary tract symptoms (LUTS) suggestive of benign prostatic hyperplasia (BPH). Recently, it has been reported that naftopidil suppresses human prostate tumor growth. (The product is for research purpose only.)

References


PubMed Literature


TCIMAIL
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.

The requested SDS is not available.

Please Contact Us for more information.

Specifications
C of A & Other Certificates
Please enter Lot Number Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.

The product with the lot number searched for has been discontinued and no related documentation is available.

Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.

A sample C of A for this product is not available at this time.

Analytical Charts
Please enter Lot Number Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.

The requested analytical chart is not available. Sorry for the inconvenience.

The product with the lot number searched for has been discontinued and no related documentation is available.

Other Documents

Session Status
Your session will timeout in 10 minutes. You will be redirected to the HOME page after session timeout. Please click the button to continue session from the same page. minute. You will be redirected to the HOME page after session timeout. Please click the button to continue session from the same page.

Your session has timed out. You will be redirected to the HOME page.