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CAS RN: 88678-31-3 | Product Number: L0301
Liranaftate
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Purity: >98.0%(HPLC)
Synonyms:
- O-(5,6,7,8-Tetrahydronaphthalen-2-yl) (6-Methoxypyridin-2-yl)(methyl)carbamothioate
- (6-Methoxypyridin-2-yl)(methyl)carbamothioic Acid O-(5,6,7,8-Tetrahydronaphthalen-2-yl) Ester
Product Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
|---|---|---|---|---|---|
| 50MG |
$198.00
|
Contact Us | Contact Us | 6 |
|
| 250MG |
$685.00
|
Contact Us | Contact Us | 6 |
|
* Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact TCI for lead times on items not in stock. Excludes regulated items and items that ship on ice.
* To send your quote request for bulk quantities, please click on the "Request Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | L0301 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__8H__2__0N__2O__2S = 328.43 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 88678-31-3 |
| Reaxys Registry Number | 12615149 |
| PubChem Substance ID | 354335085 |
| Merck Index (14) | 5515 |
| MDL Number | MFCD00865576 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Elemental analysis(Nitrogen) | 8.00 to 9.00 % |
| Melting point | 97.0 to 101.0 °C |
Properties (reference)
| Melting Point | 99 °C |
| Solubility in water | Insoluble |
| Solubility (soluble in) | Chloroform, Acetone, dichloromethane |
| Solubility (slightly sol. in) | Diethyl ether |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. H317 : May cause an allergic skin reaction. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P272 : Contaminated work clothing must not be allowed out of the workplace. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P302 + P352 : IF ON SKIN: Wash with plenty of soap and water. P333 + P313 : If skin irritation or rash occurs: Get medical advice/ attention. P362 : Take off contaminated clothing and wash before reuse. |
Related Laws:
| RTECS# | FD3890000 |
Transport Information:
| HS Number | 2933.39.4100 |
Application
Liranaftate: A Synthetic Thiocarbamate Antifungal Reagent
Liranaftate (piritetrate or M-732) is a chemical synthetic antifungal reagent, belonging chemically to the thiocarbamates. Although the exact mechanism of action is not entirely known, liranaftate would inhibit sterol biosynthesis at the level of squalene epoxidase which is an important enzyme in the biosynthetic pathway of the fungal membrane. Similar antifungal reagent includes tolnaftate [T3059]. (The product is for research purpose only.)
References
- Inhibitory effect of a new mycotic agent, piritetrate on ergosterol biosynthesis in pathogenic fungi
- In vitro and in vivo activities of piritetrate (M-732), a new antidermatophytic thiocarbamate
PubMed Literature
Articles/Brochures
TCIMAIL
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Safety Data Sheet (SDS)
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Specifications
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