Make sure to sign up for an account today for exclusive coupons and free shipping on orders over $75!
Maximum quantity allowed is 999
Please select the quantity
CAS RN: 910110-45-1 | Product Number: H1407
(2S)-N-[(1S)-1-(Hydroxydiphenylmethyl)-3-methylbutyl]-2-pyrrolidinecarboxamide
×
![]()
×
![(2S)-N-[(1S)-1-(Hydroxydiphenylmethyl)-3-methylbutyl]-2-pyrrolidinecarboxamide](/_ui/responsive/theme-tci/images/missing_product_zoom.jpg "(2S)-N-[(1S)-1-(Hydroxydiphenylmethyl)-3-methylbutyl]-2-pyrrolidinecarboxamide")
Purity: >98.0%(T)(HPLC)
Synonyms:
- (S)-N-[(S)-1-Hydroxy-4-methyl-1,1-diphenylpentan-2-yl]pyrrolidine-2-carboxamide
- N-[(1S)-1-(Hydroxydiphenylmethyl)-3-methylbutyl]-L-prolinamide
- Singh's Catalyst
Product Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
|---|---|---|---|---|---|
| 200MG |
$121.00
|
Contact Us | Contact Us | 6 |
|
| 1G |
$422.00
|
Contact Us | 1 | 1 |
|
* Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact TCI for lead times on items not in stock. Excludes regulated items and items that ship on ice.
* To send your quote request for bulk quantities, please click on the "Request Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | H1407 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__2__3H__3__0N__2O__2 = 366.51 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 910110-45-1 |
| Reaxys Registry Number | 10473304 |
| PubChem Substance ID | 253661520 |
| MDL Number | MFCD22200506 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 191.0 to 195.0 °C |
| Specific rotation [a]20/D | -46.0 to -49.0 deg(C=1, CHCl3) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 193 °C |
| Specific Rotation | -47° (C=1,CHCl3) |
| Solubility (soluble in) | Methanol |
GHS
Related Laws:
Transport Information:
| HS Number | 2933.99.7900 |
Application
An Efficient Chiral Organocatalyst for the Cross-aldol Reaction of Aliphatic Ketones with Aldehydes
An aldehyde (0.5 mmol) is added to a mixture of ketone (2 mmol) and Singh's catalyst (0.5 mol %) in brine (0.5 mL) at -5 °C. The reaction mixture is stirred and the progress of the reaction is monitored by TLC. After reaction is over, the reaction mixture is diluted with EtOAc (10 mL). The organic layer is separated and dried over anhydrous Na2SO4. It is purified over silica gel by column chromatography to give the aldol product.
References
- Highly Efficient Small Organic Molecules for Enantioselective Direct Aldol Reaction in Organic and Aqueous Media
- Highly Enantioselective Organocatalytic Direct Aldol Reaction in an Aqueous Medium
- Highly Enantioselective Direct Aldol Reaction Catalyzed by Organic Molecules
- Enantioselective Aldol Reactions of Aliphatic Aldehydes with Singh’s Catalyst
PubMed Literature
Articles/Brochures
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.