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CAS RN: 58-28-6 | Product Number: D6181
Desipramine Hydrochloride
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Purity: >98.0%(T)(HPLC)
Synonyms:
- 3-(10,11-Dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-methyl-1-propanamine Hydrochloride
- 3-(10,11-Dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-methylpropan-1-amine Hydrochloride
Product Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
|---|---|---|---|---|---|
| 5G |
$195.00
|
Contact Us | Contact Us | 25 |
|
| 25G |
$657.00
|
Contact Us | Contact Us | 28 |
|
* Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact TCI for lead times on items not in stock. Excludes regulated items and items that ship on ice.
* To send your quote request for bulk quantities, please click on the "Request Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | D6181 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__8H__2__2N__2·HCl = 302.85 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Hygroscopic |
| CAS RN | 58-28-6 |
| Reaxys Registry Number | 4166006 |
| MDL Number | MFCD00058108 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 212.0 to 216.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 214 °C |
| Maximum Absorption Wavelength | 250 nm (H__2O) |
| Solubility in water | Soluble |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. H336 : May cause drowsiness or dizziness. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray. P270 : Do not eat, drink or smoke when using this product. P271 : Use only outdoors or in a well-ventilated area. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. P304 + P340 + P312 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor if you feel unwell. P403 + P233 : Store in a well-ventilated place. Keep container tightly closed. P405 : Store locked up. |
Related Laws:
| RTECS# | HO0525000 |
Transport Information:
| HS Number | 2933.99.6100 |
Application
Desipramine hydrochloride: An Active Tricyclic Antidepressant
Desipramine hydrochloride, a metabolite of imipramine [I0971], is an active tricyclic antidepressant. While the precise mechanism of action of tricyclic antidepressants is unknown, many studies suggest that they restore normal levels of neurotransmitters, such as norepinephrine and serotonin, by blocking the reuptake of these substances from the synapse in the central nervous system. (The product is for research purpose only.)
References
- Clinical Pharmacokinetics of Imipramine and Desipramine
- Studies on the distinction between uptake inhibition and release of [3H] dopamine in rat brain tissue slices
- The tail suspension test: a new method for screening antidepressants in mice
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
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Specifications
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Analytical Charts
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