Make sure to sign up for an account today for exclusive coupons and free shipping on orders over $75!
Maximum quantity allowed is 999
Please select the quantity
CAS RN: 298-57-7 | Product Number: C3459
Cinnarizine
×
![]()
×
Purity: >98.0%(HPLC)(N)
Synonyms:
- 1-Cinnamyl-4-diphenylmethylpiperazine
- 1-(Diphenylmethyl)-4-(3-phenyl-2-propenyl)piperazine
- 1-Benzhydryl-4-cinnamylpiperazine
Product Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
|---|---|---|---|---|---|
| 10G |
$47.00
|
1 | Contact Us | 33 |
|
| 50G |
$134.00
|
Contact Us | Contact Us | 6 |
|
* Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact TCI for lead times on items not in stock. Excludes regulated items and items that ship on ice.
* To send your quote request for bulk quantities, please click on the "Request Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | C3459 |
| Purity / Analysis Method | >98.0%(HPLC)(N) |
| Molecular Formula / Molecular Weight | C__2__6H__2__8N__2 = 368.52 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 298-57-7 |
| Reaxys Registry Number | 626120 |
| PubChem Substance ID | 354335235 |
| Merck Index (14) | 2305 |
| MDL Number | MFCD00056037 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(with Total Nitrogen) | min. 98.0 % |
| Melting point | 117.0 to 121.0 °C |
Properties (reference)
| Melting Point | 119 °C |
GHS
Related Laws:
Transport Information:
| HS Number | 2933.59.2100 |
Application
Cinnarizine: A Calcium Channel and a Histamine H1 Receptor Antagonist
Cinnarizine, a piperazine derivative, is a calcium channel and a histamine H1 receptor antagonist. Cinnarizine inhibits contractions of vascular smooth muscle cells by blocking calcium channels. In addition, cinnarizine increases erythrocyte deformability and decreases blood viscosity. Cinnarizine also exhibits anticonvulsant properties. Cinnarizine is used widely in the treatment of circulatory disorders. However, cinnarizine-induced parkinsonism has been reported. (The product is for research purpose only.)
References
- Flunarizine. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic use
- Effects of cinnarizine, a calcium antagonist that produces human parkinsonism, in parkin knock out mice
- Oral bioavailability of cinnarizine in dogs: Relation to SNEDDS droplet size, drug solubility and in vitro precipitation
- Simultaneous determination of cinnarizine and domepiridone maleate from tablet dosage form by reverse phase ion pair high performance liquid chromatography
- Validation of a solid-phase extraction and liquid chromatography-electrospray tandem mass spectrometric method for the determination of nine basic pharmaceuticals in wastewater and surface water samples
PubMed Literature
Articles/Brochures
TCIMAIL
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.