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CAS RN: 330942-05-7 | Product Number: B6398
Betrixaban
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Purity: >95.0%(HPLC)(qNMR)
Synonyms:
- N-(5-Chloropyridin-2-yl)-2-[4-(N,N-dimethylcarbamimidoyl)benzamido]-5-methoxybenzamide
Product Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
|---|---|---|---|---|---|
| 250MG |
$275.00
|
Contact Us | Contact Us | 32 |
|
* Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact TCI for lead times on items not in stock. Excludes regulated items and items that ship on ice.
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| Product Number | B6398 |
| Purity / Analysis Method | >95.0%(HPLC)(qNMR) |
| Molecular Formula / Molecular Weight | C__2__3H__2__2ClN__5O__3 = 451.91 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive |
| CAS RN | 330942-05-7 |
| Reaxys Registry Number | 15486817 |
| MDL Number | MFCD16038040 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Purity(qNMR) | min. 95.0 % |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 216 °C |
GHS
Related Laws:
Transport Information:
| HS Number | 2933.39.9200 |
Application
Betrixaban: A Direct Inhibitor of the Factor Xa
Betrixaban (PRT054021) is an oral inhibitor of the serine protease Factor Xa (FXa) that selectively blocks the active site of FXa. FXa activates pro-thrombin in the blood coagulation cascade. Betrixaban decreases thrombin generation by directly inhibiting FXa, but it has no direct effect on platelet aggregation. (The product is for research purpose only.)
References
- Discovery of betrixaban (PRT054021), N-(5-chloropyridin-2-yl)-2-(4-(N,N-dimethylcarbamimidoyl)benzamido)-5-methoxybenzamide, a highly potent, selective, and orally efficacious factor Xa inhibitor
- Profile of betrixaban and its potential in the prevention and treatment of venous thromboembolism (a review)
- Comparative pharmacodynamics and pharmacokinetics of oral direct thrombin and factor Xa inhibitors in development (a review)
Product Documents (Note: Some products will not have analytical charts available.)
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Specifications
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