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CAS RN: 546-43-0 | Product Number: A3585
Alantolactone
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Purity: >95.0%(GC)
Synonyms:
- (3aR,5S,8aR,9aR)-5,8a-Dimethyl-3-methylene-3a,5,6,7,8,8a,9,9a-octahydronaphtho[2,3-b]furan-2(3H)-one
Product Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
|---|---|---|---|---|---|
| 250MG |
$321.00
|
Contact Us | Contact Us | 27 |
|
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| Product Number | A3585 |
| Purity / Analysis Method | >95.0%(GC) |
| Molecular Formula / Molecular Weight | C__1__5H__2__0O__2 = 232.32 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Frozen (<0°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Light Sensitive,Moisture Sensitive,Heat Sensitive |
| CAS RN | 546-43-0 |
| Reaxys Registry Number | 5266481 |
| MDL Number | MFCD00274568 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(GC) | min. 95.0 % |
| Melting point | 80.0 to 84.0 °C |
| Specific rotation | +185 to +200 deg(C=1, CHCl3) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 83 °C |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H317 : May cause an allergic skin reaction. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray. P280 : Wear protective gloves. P272 : Contaminated work clothing must not be allowed out of the workplace. P302 + P352 : IF ON SKIN: Wash with plenty of soap and water. P333 + P313 : If skin irritation or rash occurs: Get medical advice/ attention. P363 : Wash contaminated clothing before reuse. |
Related Laws:
| RTECS# | QL0844500 |
Transport Information:
| HS Number | 2932.20.5050 |
Application
Alantolactone: A Bioactive Sesquiterpene Lactone with Anticancer Activity
Alantolactone and isoalantolactone [I0835] are sesquiterpene lactones found in many medicinal plants such as Inula helenium, Inula japonica L., Aucklandia lappa, Inula racemosa, and Radix inulae. Alantolactone and isoalantolactone have been reported to have diverse biological activities including anti-inflammatory, antimicrobial, antioxidant, and anticancer properties without significant toxicity. (The product is for research purpose only.)
References
- Alantolactone suppresses inducible nitric oxide synthase and cyclooxygenase-2 expression by down-regulating NF-κB, MAPK and AP-1 via the MyD88 signaling pathway in LPS-activated RAW 264.7 cells
- Alantolactone induces apoptosis in glioblastoma cells via GSH depletion, ROS generation, and mitochondrial dysfunction
- Targeting apoptosis pathways in cancer with alantolactone and isoalantolactone (a review)
- A comprehensive review of anticancer mechanisms of action of Alantolactone
Product Documents (Note: Some products will not have analytical charts available.)
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Specifications
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