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CAS RN: 82248-59-7 | Product Number: A2357
Atomoxetine Hydrochloride
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Purity: >98.0%(T)(HPLC)
Synonyms:
- (R)-N-Methyl-3-(2-methylphenoxy)-3-phenylpropylamine Hydrochloride
- (R)-Tomoxetine Hydrochloride
Product Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
|---|---|---|---|---|---|
| 100MG |
$90.00
|
2 | 1 | ≥60 |
|
| 1G |
$511.00
|
1 | Contact Us | 33 |
|
* Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact TCI for lead times on items not in stock. Excludes regulated items and items that ship on ice.
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| Product Number | A2357 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__7H__2__1NO·HCl = 291.82 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Frozen (<0°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 82248-59-7 |
| Related CAS RN | 83015-26-3 |
| Reaxys Registry Number | 5318974 |
| PubChem Substance ID | 125307825 |
| Merck Index (14) | 863 |
| MDL Number | MFCD06410992 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 167.0 to 171.0 °C |
| Specific rotation [a]20/D | -41.0 to -44.0 deg(C=1, MeOH) |
Properties (reference)
| Melting Point | 169 °C |
| Specific Rotation | -42° (C=1,MeOH) |
| Solubility (soluble in) | Methanol |
GHS
Related Laws:
Transport Information:
| HS Number | 2921.49.5000 |
Application
Atomoxetine Hydrochloride: A Selective Noradrenaline (Norepinephrine) Reuptake Inhibitor
Atomoxetine hydrochloride is a selective noradrenaline (norepinephrine, [A0906]) reuptake inhibitor (NRI). The selective inhibitions of the noradrenaline transporter (NAT) help to reverse the depletion of neurotransmitters at the synapse. There is evidence to suggest that atomoxetine shows beneficial effect for the treatment of attention-deficit/hyperactivity disorder (ADHD), but the precise mechanism is not fully understood. (The product is for research purpose only.)
References
- Atomoxetine increases extracellular levels of norepinephrine and dopamine in prefrontal cortex of rat: a potential mechanism for efficacy in Attention Deficit/Hyperactivity Disorder
- Atomoxetine: a review of its use in adults with attention deficit hyperactivity disorder
- The neuropharmacology of ADHD drugs in vivo: Insights on efficacy and safety (a review)
- A quality by design approach to impurity method development for atomoxetine hydrochloride (LY139603)
PubMed Literature
Articles/Brochures
TCIMAIL
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
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Specifications
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