Maximum quantity allowed is 999
请选择数量
CAS RN: 2646-38-0 | 產品號碼: S0941
Sodium Chenodeoxycholate
×
![]()
×
* 以上價格已含運費關稅等但一些需要海運以及乾冰運輸的產品除外,詳情請與
當地經銷商
洽詢。
* TCI會時常優化儲存條件,儲存溫度請以在線目錄為準，敬請留意。
| 產品號碼 | S0941 |
| 純度/分析方法 | >97.0%(GC) |
| 分子式 / 分子量 | C__2__4H__3__9NaO__4 = 414.56 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件 | Room Temperature (Recommended in a cool and dark place, <15°C) |
| 包裝和容器 | 1G-Glass Bottle with Plastic Insert （閲覽圖片）, 200MG-Glass Bottle with Plastic Insert （閲覽圖片） |
| CAS RN | 2646-38-0 |
| Reaxys-RN | 4898788 |
| PubChem Substance ID | 354333736 |
| MDL編號 | MFCD00065452 |
產品規格
| Appearance | White to Almost white powder to crystal |
| Purity(GC) | min. 97.0 % |
| Purity(Nonaqueous Titration) | min. 96.0 % |
性質
| 熔點 | 298 °C(dec.) |
GHS
| 圖形表示 |
|
| 信號詞 | Warning |
| 危險性說明 | H302 : Harmful if swallowed. |
| 防範說明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
相關法規
| RTECS # | FZ2231000 |
運輸資料
| HS編碼* | 2918.19-000 |
Application
Chenodeoxycholic Acid: A Naturally Occurring Bile Acid Having Suppressing Effects of Cholesterol and Cholic Acid Synthesis
Sodium chenodeoxycholate, a sodium salt of chenodeoxycholic acid, is a naturally occurring bile acid. Sodium chenodeoxycholate inhibits HMG-CoA-reductase and cholesterol-7α-hydroxylase, which are the rate-limiting step enzyme in cholesterol [C0318] and cholic acid [C0324] synthesis, respectively. Therefore, sodium chenodeoxycholate suppresses hepatic synthesis of both cholesterol and cholic acid, gradually replacing chenodeoxycholic acid in an expanded bile acid pool. In clinical use, these actions would contribute to gradual dissolution of cholesterol gallstones. (The product is for research purpose only.)
References
- Induced alterations in the rate-limiting enzymes of hepatic cholesterol and bile acid synthesis in the hamster.
- The effect of chenodeoxycholic acid (CDCA) on cholesterol absorption
- Chenodeoxycholic acid: a review of its pharmacological properties and therapeutic use
- Detoxification of lithocholic acid, a toxic bile acid: relevance to drug hepatotoxicity (a review)
考研文獻