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CAS RN: 152-95-4 | 產品號碼: S0835
產品號碼 | S0835 |
純度/分析方法 | >98.0%(HPLC) |
分子式 / 分子量 | C__2__1H__2__0O__1__0 = 432.38 |
外觀與形狀(20°C) | Solid |
儲存條件 | Room Temperature (Recommended in a cool and dark place, <15°C) |
包裝和容器 | 100MG-Glass Bottle with Plastic Insert (閲覽圖片) |
CAS RN | 152-95-4 |
Reaxys-RN | 63197 |
PubChem Substance ID | 125307426 |
MDL編號 | MFCD01075138 |
產品規格
Appearance | Light yellow to Brown powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Specific rotation [a]20/D | -17.0 to -22.0 deg(C=1, Pyridine) |
NMR | confirm to structure |
性質
熔點 | 297 °C |
比旋光 [α]D | -18° (C=1,Pyridine) |
Maximum Wavelength | 271(MeOH) nm |
GHS
相關法規
運輸資料
HS編碼* | 2938.90-000 |
Application
Sophoricoside: An Isoflavone Glycoside with Inhibitory Effects of IL-5, IL-3, IL-6, and COX-2 Activities
Sophoricoside is an isoflavone glycoside found in Sophora japonica L. (Leguminosae family) which is a traditional Chinese medicinal herb used as hemostatic agent.1) Pharmacological studies have demonstrated that Sophora japonica L. has antitumor and antifertility activities.1) It has been reported that sophoricoside exhibits inhibitory effects on interleukin-5 (IL-5), IL-3, IL-6, and COX-2 activities.2-5) (The product is for research purpose only.)
References
- 1) Determination of sophoricoside in rat plasma by HPLC and its application to pharmacokinetic studies
- 2) Sophoricoside analogs as the IL-5 inhibitors from Sophora japonica
- 3) Differential inhibitory effects of sophoricoside analogs on bioactivity of several cytokines
- 4) Anti-inflammatory mode of isoflavone glycoside sophoricoside by inhibition of interleukin-6 and cyclooxygenase-2 in inflammatory response
- 5) Anti-inflammatory action of legume isoflavonoid sophoricoside through inhibition on cyclooxygenase-2 activity
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