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CAS RN: 179474-81-8 | 產品號碼: P2467
產品規格
| Appearance | White to Light yellow to Light orange powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Water | max. 7.0 % |
| NMR | confirm to structure |
性質
| 熔點 | 92 °C |
GHS
| 圖形表示 |
|
| 信號詞 | Warning |
| 危險性說明 | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| 防範說明 | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
相關法規
| RTECS # | DF6472550 |
運輸資料
| HS編碼* | 2934.99-000 |
Application
Prucalopride: A Selective Serotonin Type 4 (5-HT4) Receptor Agonist
Prucalopride, a dihydrobenzofuran-carboxamide derivative, is a selective serotonin type 4 (5-HT4) receptor agonist that stimulates colonic peristalsis, which increases bowel motility. It has been reported that prucalopride is devoid of effects mediated via other receptors in vitro (such as 5-HT1B, 5-HT1D, and 5-HT2B) that leading to adverse cardiovascular events. (The product is for research purpose only.)
References
- The in vitro pharmacological profile of prucalopride, a novel enterokinetic compound
- Role of prucalopride, a serotonin (5-HT4) receptor agonist, for the treatment of chronic constipation (a review)
- 5-HT4 receptor agonists: similar but not the same (a review)
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