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CAS RN: 147526-32-7 | 產品號碼: P2071
Pitavastatin Calcium (contains 15% Water at maximum)
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| 包裝 | 價格 | 同一天 | 2-3个工作日 | 左側以上貨期 |
貨期資訊
|
|---|---|---|---|---|---|
| 250MG |
NT$11,560
|
0 | 0 | 下單後約4-5週內可以出貨 |
* 以上價格已含運費關稅等但一些需要海運以及乾冰運輸的產品除外,詳情請與
當地經銷商
洽詢。
* TCI會時常優化儲存條件,儲存溫度請以在線目錄為準，敬請留意。
| 產品號碼 | P2071 |
| 純度/分析方法 | >98.0%(T)(HPLC) |
| 分子式 / 分子量 | C__5__0H__4__6CaF__2N__2O__8 = 881.00 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件 | Room Temperature (Recommended in a cool and dark place, <15°C) |
| 儲存在惰性氣體下 | Store under inert gas |
| 應避免的情況 | Air Sensitive |
| CAS RN | 147526-32-7 |
| Reaxys-RN | 7965530 |
| Merck Index(14) | 7508 |
| MDL編號 | MFCD01937979 |
產品規格
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Chelometric Titration) | min. 98.0 %(calcd.on anh.substance) |
| Specific rotation | +20.0 to +24.0 deg(C=1, CH3CN/H2O) |
| Water | max. 15.0 % |
| NMR | confirm to structure |
性質
| 比旋光 [α]D | 23.2° (C=1,CH3CN aq.) |
| 水溶性 | Insoluble |
| 溶解性（不溶於） | Ethanol |
GHS
| 圖形表示 |
|
| 信號詞 | Warning |
| 危險性說明 | H302 : Harmful if swallowed. H361 : Suspected of damaging fertility or the unborn child. H362 : May cause harm to breast-fed children. |
| 防範說明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P263 : Avoid contact during pregnancy and while nursing. P260 : Do not breathe dusts or mists. P270 : Do not eat, drink or smoke when using this product. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. P405 : Store locked up. |
相關法規
| RTECS # | MJ8047045 |
運輸資料
| HS編碼* | 2933.49-000 |
Application
Pitavastatin Calcium: An HMG-CoA Reductase Inhibitor
Pitavastatin calcium (NK-104) is an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, also known as "a statin". The reductase catalyzes the conversion of HMG-CoA to mevalonate, a rate-limiting step in the biosynthetic pathway for cholesterol in the liver. Pitavastatin, an HMG-CoA reductase inhibitor, inhibits cholesterol biosynthesis and reduces plasma triglyceride and total cholesterol levels in animals. (The product is for research purpose only.)
References
- Pharmacological profile of a novel synthetic inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductase
- Hypolipidemic effect of NK-104, a potent HMG-CoA reductase inhibitor, in guinea pigs
- Relative Induction of mRNA for HMG CoA Reductase and LDL Receptor by Five Different HMG-CoA Reductase Inhibitors in Cultured Human Cells
- NK-104: a novel synthetic HMG-CoA reductase inhibitor (a review)
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