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CAS RN: 128607-22-7 | 產品號碼: O0441
Ospemifene
| 包裝 | 價格 | 同一天 | 2-3个工作日 |
|---|---|---|---|
| 100MG |
NT$4,360
|
10 | 7 |
| 1G |
NT$28,200
|
14 | 19 |
* 以上價格已含運費關稅等但一些需要海運以及乾冰運輸的產品除外,詳情請與
當地經銷商
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產品規格
| Appearance | White to Almost white powder to crystal |
| Purity(GC) | min. 98.0 % |
性質
GHS
| 圖形表示 |
|
| 信號詞 | Warning |
| 危險性說明 | H361 : Suspected of damaging fertility or the unborn child. |
| 防範說明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P405 : Store locked up. |
相關法規
運輸資料
| HS編碼* | 2909.49-000 |
Application
選択的エストロゲン受容体調節剤 (SERM)，オスペミフェン
Ospemifene (FC1271a) was first reported as a metabolite of toremifene [T2832] which is an antiestrogen and a hormonal antitumor agent. Ospemifene is the first non-hormonal estrogen receptor agonist/antagonist or selective estrogen receptor modulator (SERM). It specifically binds to the estrogen receptor α and β with affinity closely similar to that of toremifene and tamoxifen [T2510]. Ospemifene is currently used for treatment of vulvovaginal atrophy (VVA). In addition, the antiestrogenic activity of ospemifene in several breast cancer animal models has been reported. (The product is for research purpose only.)
References
- Metabolism of toremifene in the rat
- Selective estrogenic effects of a novel triphenylethylene compound, FC1271a, on bone, cholesterol level, and reproductive tissues in intact and ovariectomized rats
- Pharmacokinetics of selective estrogen receptor modulators (a review)
- Selective estrogen receptor modulators for postmenopausal osteoporosis: current state of development (a review)
- Tissue selectivity of ospemifene: Pharmacologic profile and clinical implications (a review)
- Ospemifene, vulvovaginal atrophy, and breast cancer (a review)
考研文獻
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